Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018039662) RAPID ISOLATION OF CYCLOTRON-PRODUCED GALLIUM-68
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/039662 International Application No.: PCT/US2017/048823
Publication Date: 01.03.2018 International Filing Date: 28.08.2017
IPC:
A61K 51/02 (2006.01) ,A61K 51/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
02
characterised by the carrier
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
12
characterised by a special physical form, e.g. emulsion, microcapsules, liposomes
Applicants:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH [US/US]; 200 First Street SE Rochester, MN 55905, US
Inventors:
PANDEY, Mukesh, K.; US
DEGRADO, Timothy, R.; US
Agent:
ROCHE, Richard, T.; US
Priority Data:
62/380,18326.08.2016US
Title (EN) RAPID ISOLATION OF CYCLOTRON-PRODUCED GALLIUM-68
(FR) ISOLEMENT RAPIDE DE GALLIUM-68 PRODUIT PAR CYCLOTRON
Abstract:
(EN) Methods for rapid isolation of radionuclides (e.g., 68Ga) produced using a cyclotron and methods for recycling of the parent isotope (e.g., 68Zn) are disclosed. In one version of the method, a solution including a radionuclide (e.g., 68Ga) is created from a target including cations (e.g., 68Zn). The solution including the radionuclide is passed through a first column including a sorbent comprising a hydroxamate resin to adsorb the radionuclide on the sorbent, and the radionuclide is eluted off the sorbent. The cations (e.g., 68Zn) are recovered from a recovery solution that has passed through the first column by passing the recovery solution through a second column including a second sorbent comprising a cation exchange resin.
(FR) La présente invention concerne des procédés d’isolement rapide de radionucléides (par exemple, Ga68) produits à l'aide d'un cyclotron et des procédés de recyclage de l’isotope parent (par exemple, Zn68). Dans une version du procédé, une solution comprenant un radionucléide (par exemple, Ga68) est créée à partir d’une cible comprenant des cations (par exemple, Zn68). La solution comprenant le radionucléide passe à travers une première colonne comprenant un sorbant comportant une résine hydroxamate en vue d'adsorber le radionucléide sur le sorbant, et le radionucléide est élué du sorbant. Les cations (par exemple, Zn68) sont récupérés d’une solution de récupération qui est passée à travers la première colonne en faisant passer la solution de récupération à travers une seconde colonne comprenant un second sorbant comportant une résine échangeuse de cations.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)