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1. (WO2018039283) PEPTIDES AND METHODS OF USE THEREOF
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Pub. No.: WO/2018/039283 International Application No.: PCT/US2017/048084
Publication Date: 01.03.2018 International Filing Date: 22.08.2017
IPC:
C07K 16/40 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
40
against enzymes
Applicants:
FRED HUTCHINSON CANCER RESEARCH CENTER [US/US]; 1100 Fairview Avenue North Seattle, WA 98109, US
Inventors:
OLSON, James; US
SOTTERO, Theo; US
GIRARD, Emily; US
MHYRE, Andrew; US
CORRENTI, Colin; US
MEHLIN, Christopher; US
GEWE, Mesfin, Mulugeta; US
HOPPING, Gene, Gregory; US
Agent:
RAMANATHAN, Renuka; US
ADVANI, Raj; US
AGRAWAL, Trisha; US
ALEMOZAFAR, Ali; US
ALMEDA, Dariela; US
Priority Data:
62/378,17222.08.2016US
Title (EN) PEPTIDES AND METHODS OF USE THEREOF
(FR) PEPTIDES ET LEURS PROCÉDÉS D'UTILISATION
Abstract:
(EN) Peptides that home, migrate to, distribute to, accumulate in, are directed to, and/or bind to tumors, cancerous tissues and cells thereof are disclosed. Pharmaceutical compositions and uses for peptides, peptide- active agent complexes comprising such peptides, or peptide-detectable agent complexes comprising such peptides are additionally disclosed. Such compositions can be formulated for targeted or untargeted delivery of a drug to a target region, tissue, structure or cell. Targeted compositions of the disclosure can deliver peptide, peptide- active agent complexes, or peptide-detectable agent complexes to target regions, tissues, structures or cells targeted by the peptide.
(FR) L'invention concerne des peptides qui, résident dans, migrent vers, se diffusent vers, s'accumulent dans, sont dirigés vers, et/ou se lient à des tumeurs, des tissus cancéreux et des cellules de ceux-ci. L'invention concerne en outre des compositions pharmaceutiques et des utilisations de peptides, de complexes agents actifs-peptides comprenant de tels peptides, ou des complexes d'agents détectables par des peptides comprenant de tels peptides. De telles compositions peuvent être formulées pour l'administration ciblée ou non ciblée d'un médicament sur une région, un tissu, une structure ou une cellule cibles. Les compositions ciblées de l'invention peuvent administrer un peptide ou des complexes peptides-agents actifs sur des régions, des tissus, des structures ou des cellules cibles ciblés par le peptide.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)