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1. (WO2018039205) PEPTIDE VACCINES AND DURVALUMAB FOR TREATING BREAST CANCER
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/039205    International Application No.:    PCT/US2017/047973
Publication Date: 01.03.2018 International Filing Date: 22.08.2017
IPC:
A61K 39/00 (2006.01), A61P 35/00 (2006.01)
Applicants: ONCOPEP, INC. [US/US]; 520 Boston Street North Andover, MA 01845 (US)
Inventors: PETERKIN, Doris; (US).
COHEN, Marc A.; (US)
Agent: COLLAZO, Diana M.; (US)
Priority Data:
62/378,416 23.08.2016 US
Title (EN) PEPTIDE VACCINES AND DURVALUMAB FOR TREATING BREAST CANCER
(FR) VACCINS PEPTIDIQUES ET DURVALUMAB POUR LE TRAITEMENT DU CANCER DU SEIN
Abstract: front page image
(EN)The disclosure features, inter alia, combination therapies comprising durvalumab and one or more immunogenic XBP1-, CD138-, and CS1 -derived peptides. The therapies herein can be used, e.g., for inducing an immune response in a subject having a solid tumor, and treating a solid tumor, e.g., breast cancer, e.g., triple negative breast cancer.
(FR)Les caractéristiques de l'invention,entre autres, des polythérapies comprenant du durvalumab et un ou plusieurs peptides dérivés de XBP1, CD138 et CS1 immunogènes. Les thérapies de l'invention peuvent être utilisées, par exemple, pour induire une réponse immunitaire chez un sujet ayant une tumeur solide, et traiter une tumeur solide, par exemple, le cancer du sein, par exemple le cancer du sein triple négatif.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)