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1. (WO2018039159) MUSCARINIC M2-ANTAGONIST COMBINATION

Pub. No.:    WO/2018/039159    International Application No.:    PCT/US2017/047897
Publication Date: Fri Mar 02 00:59:59 CET 2018 International Filing Date: Wed Aug 23 01:59:59 CEST 2017
IPC: A61K 31/13
A61K 31/33
A61K 31/44
A61K 31/439
A61K 31/445
A61K 31/495
A61P 25/18
A61P 25/28
Applicants: CHASE PHARMACEUTICALS CORPORATION
Inventors: CHASE, Thomas N.
CLARENCE-SMITH, Kathleen E.
Title: MUSCARINIC M2-ANTAGONIST COMBINATION
Abstract:
A combination of a M2-receptor antagonist and a non-anticholinergic antiemetic agent, and optionally an anticholinesterase inhibitor, to treat hypocholinergic disorders such as Alzheimer type dementia, schizophrenia, schizophrenia associated dementia, and schizoaffective disorders.