Search International and National Patent Collections

1. (WO2018039157) ANTIVIRAL PRODRUGS OF TENOFOVIR

Pub. No.:    WO/2018/039157    International Application No.:    PCT/US2017/047892
Publication Date: Fri Mar 02 00:59:59 CET 2018 International Filing Date: Wed Aug 23 01:59:59 CEST 2017
IPC: A61K 31/52
A61P 31/12
C07F 9/6561
Applicants: MERCK SHARP & DOHME CORP.
IDENIX PHARMACEUTICALS LLC
DA COSTA, Daniel
DOUSSON, Cyril, B.
DUKHAN, David
PAPARIN, Jean-Laurent
RAHALI, Houcine
RAHEEM, Izzat
Inventors: DA COSTA, Daniel
DOUSSON, Cyril, B.
DUKHAN, David
PAPARIN, Jean-Laurent
RAHALI, Houcine
RAHEEM, Izzat
Title: ANTIVIRAL PRODRUGS OF TENOFOVIR
Abstract:
Compounds of Formula I: and pharmaceutically acceptable salts and co-crystals thereof are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.