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1. (WO2018039145) SINGLE GUIDE RNA, CRISPR/CAS9 SYSTEMS, AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/039145    International Application No.:    PCT/US2017/047861
Publication Date: 01.03.2018 International Filing Date: 21.08.2017
IPC:
C12N 15/63 (2006.01), C12N 15/85 (2006.01), C12N 9/22 (2006.01), C12Q 1/68 (2006.01)
Applicants: AVELLINO LAB USA, INC. [US/US]; 1505 Adams Drive Menlo Park, CA 94025 (US)
Inventors: MOORE, Tara; (US).
NESBIT, Andrew; (US).
COURTNEY, David; (US).
CHRISTIE, Katie; (US).
LEE, Gene; (US)
Agent: LEE, Janice, H.; (US).
KOO, Tae-Woong; (US)
Priority Data:
62/377,586 20.08.2016 US
62/462,808 23.02.2017 US
62/501,750 05.05.2017 US
Title (EN) SINGLE GUIDE RNA, CRISPR/CAS9 SYSTEMS, AND METHODS OF USE THEREOF
(FR) ARN GUIDE UNIQUE, SYSTÈMES CRISPR/CAS9 ET LEURS PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)The present disclosure relates to single guide RNA (sgRNA), Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR associate protein 9 (Cas9) system, and methods of use thereof for preventing, ameliorating or treating corneal dystrophies.
(FR)La présente invention concerne un ARN guide unique (sgRNA), un système (Cas9) protéine 9 associée à de courtes répétitions palindromiques regroupées et régulièrement espacées (CRISPR)/CRISPR/Cas9, et des procédés d'utilisation de ceux-ci pour la prévention, le soulagement ou le traitement de dystrophies cornéennes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)