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1. (WO2018038623) IMPROVEMENTS IN PARASITE TREATMENTS

Pub. No.:    WO/2018/038623    International Application No.:    PCT/NZ2017/050111
Publication Date: Fri Mar 02 00:59:59 CET 2018 International Filing Date: Fri Aug 18 01:59:59 CEST 2017
IPC: A61K 31/429
A61P 3/10
A61K 31/365
A01N 43/90
A01N 43/74
Applicants: DONAGHYS LIMITED
Inventors: YERITSYAN, Karen
Title: IMPROVEMENTS IN PARASITE TREATMENTS
Abstract:
Described herein are formulations and methods of manufacture providing levamisole in a salt form with an additional anthelmintic having a different class of activity. The formulation uses a multi- solvent system to produce a topically applied formulation with all compounds in solution. In one aspect a formulation is described comprising in solution a mixture of a therapeutically effective amount of levamisole salt dissolved in at least one inorganic solvent; and a therapeutically effective amount of at least one additional anthelmintic compound with a different class of activity to levamisole, the at least one additional anthelmintic compound being substantially lipophilic and being dissolved in at least one organic solvent. A related veterinary medicament and method of treatment of parasites are also described.