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1. (WO2018038465) SKIN-WHITENING COMPOSITION CONTAINING 3-CHLORO-N-[TRANS-4-(METHYLAMINO)CYCLOHEXYL]-N-[[3-(4-PYRIDINYL)PHENYL]METHYL]BENZO[B]THIOPHENE-2-CARBOXAMIDE
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Pub. No.: WO/2018/038465 International Application No.: PCT/KR2017/009033
Publication Date: 01.03.2018 International Filing Date: 18.08.2017
IPC:
A61K 31/381 (2006.01) ,A61K 31/4418 (2006.01) ,A61K 8/49 (2006.01) ,A61Q 19/02 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
38
having sulfur as a ring hetero atom
381
having five-membered rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4418
having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
49
containing heterocyclic compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19
Preparations for care of the skin
02
for chemically bleaching or whitening the skin
Applicants: AMOREPACIFIC CORPORATION[KR/KR]; 106, Hangang-daero, Yongsan-gu, Seoul 04386, KR
Inventors: CHOI, Hyun Jung; KR
BAE, Il Hong; KR
KIM, Hyoung June; KR
LEE, Young Jin; KR
LEE, Tae Ryong; KR
CHO, Dong-Hyung; KR
Agent: KIM, Sun-young; KR
Priority Data:
10-2016-010787324.08.2016KR
Title (EN) SKIN-WHITENING COMPOSITION CONTAINING 3-CHLORO-N-[TRANS-4-(METHYLAMINO)CYCLOHEXYL]-N-[[3-(4-PYRIDINYL)PHENYL]METHYL]BENZO[B]THIOPHENE-2-CARBOXAMIDE
(FR) COMPOSITION DE BLANCHIMENT DE LA PEAU CONTENANT DU 3-CHLORO-N-[TRANS-4-(MÉTHYLAMINO)CYCLOHEXYL]-N-[[3-(4-PYRIDINYL)PHÉNYL]MÉTHYL]BENZO[B]THIOPHÈNE-2-CARBOXAMIDE
(KO) 3-클로로-N-[트랜스-4-(메틸아미노)사이클로헥실]-N-[[3-(4-피리디닐)페닐]메틸]벤조[b]티오펜-2-카복사마이드를 포함하는 피부 미백용 조성물
Abstract:
(EN) One aspect of the present invention relates to a skin-whitening composition containing, as an active ingredient, 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide, optical or stereoscopic isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof, or solvates thereof. Through the one aspect of the present invention, a novel whitening material can be provided to consumers and development of skin whitening-related industries can be promoted.
(FR) Un aspect de la présente invention concerne une composition de blanchiment de la peau contenant comme principe actif du 3-chloro-N-[trans-4-(méthylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phényl]méthyl]benzo[b]thiophène-2-carboxamide, des isomères optiques ou stéréoscopiques de ce dernier, des sels pharmaceutiquement acceptables de ce dernier, des hydrates de ce dernier, ou des solvates de ce dernier. Selon un aspect de la présente invention, un nouveau matériau de blanchiment peut être fourni à des consommateurs, et le développement d'industries liées au blanchiment de la peau peut être favorisé.
(KO) 본 발명은 일측면에서, 3-클로로-N-[트랜스-4-(메틸아미노)사이클로헥실]-N-[[3-(4-피리디닐)페닐]메틸]벤조[b]티오펜-2-카복사마이드, 이의 광학 또는 입체 이성질체, 이의 허용가능한 염, 이의 수화물, 또는 이의 용매화물을 유효성분으로 포함하는 피부 미백용 조성물에 관한 것이며, 본 발명의 일 측면을 통해 새로운 미백용 물질을 소비자에게 제공할 수 있고, 피부 미백 관련 산업의 발전을 도모할 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)