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1. (WO2018038297) NOVEL SALT OF (R)-(1-METHYLPYRROLIDIN-3-YL)METHYL(3'-CHLORO-4'-FLUORO-[1,1'-BIPHENYL]-2-YL)CARBAMATE AND CRYSTAL FORM THEREOF

Pub. No.:    WO/2018/038297    International Application No.:    PCT/KR2016/009558
Publication Date: Fri Mar 02 00:59:59 CET 2018 International Filing Date: Sat Aug 27 01:59:59 CEST 2016
IPC: C07D 207/06
A61K 31/40
Applicants: DONG-A ST CO., LTD.
동아에스티 주식회사
Inventors: KWAK, Woo Young
곽우영
SHIN, Chang-Yong
신창용
ULLAPU, Punna Reddy
울라푸푼나 레디
CHOI, Sun-Ho
최선호
LEE, Min-Jung
이민정
KIM, Ji-Su
김지수
Title: NOVEL SALT OF (R)-(1-METHYLPYRROLIDIN-3-YL)METHYL(3'-CHLORO-4'-FLUORO-[1,1'-BIPHENYL]-2-YL)CARBAMATE AND CRYSTAL FORM THEREOF
Abstract:
The present invention relates to a novel salt of (R)-(1-methylpyrrolidin-3-yl)methyl(3'-chloro-4'-fluoro-[1,1'-biphenyl]-2-yl)carbamate and a crystal form thereof. In addition, the novel salt of (R)-(1-methylpyrrolidin-3-yl)methyl(3'-chloro-4'-fluoro-[1,1'-biphenyl]-2-yl)carbamate and the crystal form thereof, according to an embodiment of the present invention, have remarkably excellent stability, hygroscopicity, and solubility.