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1. (WO2018038293) PHARMACEUTICAL COMPOSITION CONTAINING SOPHORA JAPONICA L. EXTRACT AS ACTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS

Pub. No.:    WO/2018/038293    International Application No.:    PCT/KR2016/009448
Publication Date: Fri Mar 02 00:59:59 CET 2018 International Filing Date: Fri Aug 26 01:59:59 CEST 2016
IPC: A61K 36/489
A23L 1/30
Applicants: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
경희대학교 산학협력단
Inventors: CHO, Seung-Hun
조성훈
LEE, Hwa-Young
이화영
KWON, Yongju
권용주
Title: PHARMACEUTICAL COMPOSITION CONTAINING SOPHORA JAPONICA L. EXTRACT AS ACTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS
Abstract:
The present invention relates to a pharmaceutical composition containing, as an active ingredient, a Sophora japonica L. extract, for the prevention and treatment of neurodegenerative disorders and improvement of cognitive functions. Particularly, it was confirmed that the Sophora japonica L. extract, according to the present invention, has a significant effect in an Alzheimer's Disease-causing mouse model, through a Y-maze test and a Morris water maze test, thereby confirming that the Sophora japonica L. extract could be useful as an active ingredient in the pharmaceutical composition for the prevention and treatment of neurodegenerative disorders and the improvement of cognitive functions.