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1. (WO2018038265) BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND

Pub. No.:    WO/2018/038265    International Application No.:    PCT/JP2017/030609
Publication Date: Fri Mar 02 00:59:59 CET 2018 International Filing Date: Sat Aug 26 01:59:59 CEST 2017
IPC: A61K 31/437
A61K 31/4985
A61K 31/519
A61K 31/52
A61K 31/53
A61K 31/55
A61P 1/04
A61P 9/10
A61P 11/02
A61P 11/06
A61P 17/00
A61P 17/06
A61P 19/00
A61P 19/02
A61P 21/02
A61P 25/00
A61P 25/04
A61P 25/06
A61P 25/08
A61P 25/14
A61P 25/16
A61P 25/20
A61P 25/22
A61P 25/24
A61P 25/28
A61P 25/30
A61P 25/32
A61P 25/34
A61P 25/36
A61P 29/00
A61P 35/00
A61P 35/02
A61P 37/02
A61P 37/08
A61P 43/00
C07D 487/04
C07D 519/00
Applicants: MITSUBISHI TANABE PHARMA CORPORATION
田辺三菱製薬株式会社
UBE INDUSTRIES, LTD.
宇部興産株式会社
Inventors: NAKAJIMA, Tatsuo
中島 辰雄
HAYASHI, Norimitsu
林 則充
ISHIZAWA, Kouhei
石澤 公平
TSUZAKI, Yasunori
津▲崎▼ 康則
IWAMURA, Ryo
岩村 亮
TSUBOIKE, Kazunari
坪池 一成
Title: BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND
Abstract:
The present invention provides: a novel use of a specific bicyclic nitrogenated heterocyclic compound as a PDE7 inhibitor; a novel bicyclic nitrogenated heterocyclic compound having a PDE7 inhibition activity, a method for producing the compound, a use of the compound, and a pharmaceutical composition containing the PDE7 inhibitor or the compound; and others. More specifically, the present invention provides a PDE7 inhibitor containing, as an active ingredient, a compound represented by formula (I) [wherein the symbols have the same meanings as those described in the description] or a pharmacologically acceptable salt thereof.