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1. (WO2018038255) CRYSTALS OF CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF
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Pub. No.: WO/2018/038255 International Application No.: PCT/JP2017/030528
Publication Date: 01.03.2018 International Filing Date: 25.08.2017
IPC:
C07D 401/06 (2006.01) ,A61K 31/454 (2006.01) ,A61P 21/00 (2006.01) ,A61P 25/04 (2006.01)
[IPC code unknown for C07D 401/06][IPC code unknown for A61K 31/454][IPC code unknown for A61P 21][IPC code unknown for A61P 25/04]
Applicants:
東レ株式会社 TORAY INDUSTRIES, INC. [JP/JP]; 東京都中央区日本橋室町2丁目1番1号 1-1, Nihonbashi-Muromachi 2-chome, Chuo-ku, Tokyo 1038666, JP
Inventors:
高橋 弘純 TAKAHASHI Hirozumi; JP
馬場 萌子 BABA Yoko; JP
盛田 康弘 MORITA Yasuhiro; JP
伊関 克彦 ISEKI Katsuhiko; JP
泉本 直樹 IZUMIMOTO Naoki; JP
Agent:
特許業務法人平木国際特許事務所 HIRAKI & ASSOCIATES; 東京都港区愛宕二丁目5-1 愛宕グリーンヒルズMORIタワー32階 Atago Green Hills MORI Tower 32F, 5-1, Atago 2-chome, Minato-ku, Tokyo 1056232, JP
Priority Data:
2016-16543726.08.2016JP
Title (EN) CRYSTALS OF CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF
(FR) CRISTAUX DE DÉRIVÉ D'AMINE CYCLIQUE ET UTILISATION PHARMACEUTIQUE ASSOCIÉE
(JA) 環状アミン誘導体の結晶及びその医薬用途
Abstract:
(EN) The purpose of the present invention is to provide crystals of a compound that exhibits an analgesic action against neuropathic pain and/or fibromyalgia, the crystals being useful as pharmaceuticals. The present invention provides crystals of (S)-1-(4-(dimethylamino)piperidin-1-yl)-3-hydroxy-3-(1-methyl-1H-imidazol-2-yl)propan-1-one or a pharmacologically acceptable salt thereof.
(FR) L'objectif de la présente invention est de fournir des cristaux d'un composé qui présente une action analgésique contre la douleur neuropathique et/ou la fibromyalgie, les cristaux étant utiles en tant que produits pharmaceutiques. La présente invention concerne des cristaux de (S)-1-(4- (diméthylamino) pipéridin-1-yl)-3-hydroxy-3-(1-méthyl -1 H-imidazol-2-yl) propan-1-one ou un sel pharmacologiquement acceptable de celui-ci.
(JA) 本発明は、神経障害性疼痛及び/又は線維筋痛症に対して鎮痛作用を示す化合物の医薬品として有用な結晶を提供することを目的としている。本発明は、(S)-1-(4-(ジメチルアミノ)ピペリジン-1-イル)-3-ヒドロキシ-3-(1-メチル-1H-イミダゾール-2-イル)プロパン-1-オン又はその薬理学的に許容される塩の結晶を提供する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)