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1. (WO2018037045) FUSION PEPTIDES WITH ANTIGENS LINKED TO SHORT FRAGMENTS OF INVARIANT CHAIN (CD74)

Pub. No.:    WO/2018/037045    International Application No.:    PCT/EP2017/071232
Publication Date: Fri Mar 02 00:59:59 CET 2018 International Filing Date: Thu Aug 24 01:59:59 CEST 2017
IPC: C07K 14/705
A61K 39/00
C12N 15/62
Applicants: GLAXOSMITHKLINE BIOLOGICALS SA
UNIVERSITY OF COPENHAGEN
Inventors: BASSI, Maria Rosaria
CORTESE, Riccardo
D'ALISE, Anna Morena
FOLGORI, Antonella
HOLST, Peter Johannes
NICOSIA, Alfredo
Title: FUSION PEPTIDES WITH ANTIGENS LINKED TO SHORT FRAGMENTS OF INVARIANT CHAIN (CD74)
Abstract:
The present application provides inter alia a fusion protein comprising a polypeptide wherein the polypeptide consists of a fragment of invariant chain which is operably linked to an antigenic sequence and wherein the fragment of invariant chain consists of a portion of residues 17-97 of SEQ ID NO: 1, wherein the portion comprises at least 5 contiguous residues from residues 77-92 of SEQ ID NO: 1.