Search International and National Patent Collections

1. (WO2018036942) NEW DIFLUOROKETAMIDE DERIVATIVES AS HTRA1 INHIBITORS

Pub. No.:    WO/2018/036942    International Application No.:    PCT/EP2017/070985
Publication Date: Fri Mar 02 00:59:59 CET 2018 International Filing Date: Tue Aug 22 01:59:59 CEST 2017
IPC: C07D 401/12
C07D 207/277
C07K 5/08
A61P 27/02
Applicants: F. HOFFMANN-LA ROCHE AG
HOFFMANN-LA ROCHE INC.
Inventors: HORNSPERGER, Benoit
MAERKI, Hans P.
MOHR, Peter
REUTLINGER, Michael
RUDOLPH, Markus
Title: NEW DIFLUOROKETAMIDE DERIVATIVES AS HTRA1 INHIBITORS
Abstract:
The invention provides novel compounds having the general formula (I): (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, A, X and R11 are as described herein, compositions including the compounds and methods of using the compounds.