Search International and National Patent Collections

1. (WO2018036025) XYLAN-BASED DOUBLE NETWORK NANOCOMPOSITE HYDROGEL AND PREPARATION AND APPLICATION THEREOF

Pub. No.:    WO/2018/036025    International Application No.:    PCT/CN2016/109906
Publication Date: Fri Mar 02 00:59:59 CET 2018 International Filing Date: Thu Dec 15 00:59:59 CET 2016
IPC: C08F 251/00
C08F 220/56
C08F 222/38
C08F 2/44
C08K 3/04
C08K 3/16
A61L 27/44
A61L 27/52
A61L 27/58
A61K 47/36
A61K 47/32
Applicants: SOUTH CHINA UNIVERSITY OF TECHNOLOGY
华南理工大学
Inventors: REN, Junli
任俊莉
KONG, Weiqing
孔维庆
SUN, Runcang
孙润仓
HUANG, Danyang
黄丹阳
XU, Guibin
许桂彬
Title: XYLAN-BASED DOUBLE NETWORK NANOCOMPOSITE HYDROGEL AND PREPARATION AND APPLICATION THEREOF
Abstract:
The present invention belongs to the technical field of composite materials, and disclosed are a xylan-based double network nanocomposite hydrogel and the preparation and application thereof. The method includes: (1) adding a graphite oxide powder into deionized water, and ultrasonically dispersing to obtain a GO water dispersion; (2) adding xylan into deionized water, heating and stirring to obtain a xylan solution; (3) adding a water-soluble calcium salt, a reaction monomer and the xylan solution into the GO water dispersion, stirring and dispersing uniformly under an ice-bath condition, adding an initiator, a cross-linking agent and an accelerator, and stirring to mix well so as to obtain a mixed solution; (4) subjecting the mixed solution of step (3) to a drying reaction, to obtain the xylan based double network nanocomposite hydrogel. The composite hydrogel obtained in the present invention has high mechanical properties, is biodegradable and has good biocompatibility. The present invention is applicable in the field of biomedicine, such as tissue engineering, drug sustained-release, cell culture scaffold and cartilage tissue, etc.