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1. (WO2018035617) ANTIBIOTIC CARRIER CONJUGATES FOR THE TREATMENT OF KIDNEY INFECTIONS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/035617 International Application No.: PCT/CA2017/051004
Publication Date: 01.03.2018 International Filing Date: 25.08.2017
IPC:
C07K 7/08 (2006.01) ,A61K 31/545 (2006.01) ,A61K 47/64 (2017.01) ,A61K 47/68 (2017.01) ,A61P 13/12 (2006.01) ,A61P 31/04 (2006.01) ,C07K 16/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
08
having 12 to 20 amino acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
54
having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame
542
ortho- or peri-condensed with heterocyclic ring systems
545
Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula , e.g. cephalosporins, cefaclor, cephalexine
[IPC code unknown for A61K 47/64][IPC code unknown for A61K 47/68]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13
Drugs for disorders of the urinary system
12
of the kidneys
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
Applicants:
THRASOS THERAPEUTICS INC. [CA/CA]; 7171 Frederick-Banting Montreal, Québec H4S 1Z9, CA
Inventors:
LEGER, Roger; CA
ROSSERT, Jerome; US
Agent:
VICKERS, Mark F.; CA
DAMIANI, Michael; CA
EVENSON, Brandon; CA
FRITZ, Joachim T.; CA
WOOD, David; CA
ALLARD, Louis B.; CA
BEHMANN, Curtis B.; CA
BOOCOCK, Graeme R.; CA
DEKLEINE, Geoffrey; CA
GORDON, Jeff; CA
HUNG, Shin; CA
KEELER, Todd; CA
MARSMAN, Kathleen E.; CA
MUELLER-NEUHAUS, Jason R.; CA
NAUMAN, David A.; CA
PUNDSACK, Scott; CA
COGHLAN, Jeffrey; CA
RAOUL, Jennifer; CA
SILVER, Gail C.; CA
SOJONKY, Andrew D.; CA
WEBB, Timothy; CA
ZIMMERMAN, Gord; CA
Priority Data:
62/380,07326.08.2016US
Title (EN) ANTIBIOTIC CARRIER CONJUGATES FOR THE TREATMENT OF KIDNEY INFECTIONS
(FR) CONJUGUÉS DE SUPPORT ANTIBIOTIQUE POUR LE TRAITEMENT D'INFECTIONS RÉNALES
Abstract:
(EN) Provided are compounds having the Formula I : AT(RM)V-(LR)W-R3CysX1X2X3X4X5X6ProX7ThrCysR2XR3(R4)S(R5)1, (1); pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Also provided is the use of these compounds for the treatment of bacterial infections.
(FR) L'invention concerne des composés de formule I : AT(RM)V-(LR)W-R3CysX1X2X3X4X5X6ProX7ThrCysR2XR3(R4)S(R5)1, (1) ; des sels pharmaceutiquement acceptables de ceux-ci, et des compositions pharmaceutiques de ceux-ci. L'invention concerne également l'utilisation de ces composés pour le traitement des infections bactériennes.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)