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1. (WO2018035208) SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/035208    International Application No.:    PCT/US2017/047113
Publication Date: 22.02.2018 International Filing Date: 16.08.2017
IPC:
C07C 51/09 (2006.01), C07C 51/36 (2006.01), C07C 57/03 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, Twelfth Floor Oakland, CA 94607-5200 (US).
UNIVERSITY OF MASSACHUSETTS [US/US]; 70 Butterfield Terrace 3rd Floor Amherst, MA 01003-9242 (US)
Inventors: ZHANG, Guodong; (US).
HAMMOCK, Bruce; (US).
HWANG, Sung, Hee; (US).
WANG, Weicang; (US)
Agent: TRIMBLE, Alexander, R.; (US).
AMENDT, Kevin, C.; (US).
BAUER, John, A.; (US).
AZRIN, Linda, B.; (US).
ADAMS, Lisa; (US)
Priority Data:
62/375,526 16.08.2016 US
Title (EN) SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS
(FR) SYNTHÈSE ET UTILISATION D'ACIDES GRAS POLYINSATURÉS OMÉGA-HYDROXYLÉS
Abstract: front page image
(EN)The present invention provides a synthetic chemical method for preparing ω-hydroxylated polyunsaturated fatty acids (PUFAs) including 20-hydroxyeicosatetraenoic acid (20-HETE), 20-hydroxyeicosapentaenoic acid (20-HEPE), and 22-hydroxydocosahexaenoic acid (22-HDoHE) and a method of use thereof for treating cancer and macular degeneration.
(FR)La présente invention concerne un procédé chimique synthétique de préparation d'acides gras polyinsaturés co-hydroxylés (PUFA) comprenant de l'acide 20-hydroxyeicosatétraénoïque (20-HETE), l'acide 20-hydroxyeicosapentaénoïque (20-HEPE), et l'acide 22-hydroxydocosahexaénoique (22-HDoHE) et un procédé d'utilisation de celui-ci pour le traitement du cancer et de la dégénérescence maculaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)