WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Options
Query Language
Stem
Sort by:
List Length
1. (WO2018035107) STABILIZED PERTUSSIS ANTIBODIES WITH EXTENDED HALF-LIFE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/035107 International Application No.: PCT/US2017/046917
Publication Date: 22.02.2018 International Filing Date: 15.08.2017
IPC:
A61K 39/40 (2006.01) ,C07K 16/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
40
bacterial
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
12
against material from bacteria
Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM[US/US]; 201 West 7th Street Austin, TX 78701, US
SYNTHETIC BIOLOGICS, INC[US/US]; 9605 Medical Center Dr., Suite 270 Rockville, MD 20850, US
Inventors: MAYNARD, Jennifer; US
NGUYEN, Annalee; US
KALEKO, Michael; US
Agent: BYRD, Marshall P.; US
Priority Data:
62/375,34715.08.2016US
Title (EN) STABILIZED PERTUSSIS ANTIBODIES WITH EXTENDED HALF-LIFE
(FR) ANTICORPS ANTI-COQUELUCHE STABILISÉS PRÉSENTANT UNE DEMI-VIE ÉTENDUE
Abstract:
(EN) The present invention relates, in part, to modified humanized antibodies which bind the pertussis toxin protein and their use as therapeutic agents. In particular, the present invention is directed, in part, to improved humanized 1B7 and 11E6 antibodies with extended in vivo half-lives.
(FR) L'invention concerne, en partie, des anticorps humanisés modifiés qui se lient à la protéine anatoxine coquelucheuse, et leur utilisation comme agents thérapeutiques. En particulier, l'invention concerne, en partie, des anticorps 1B7 et 11E6 humanisés améliorés présentant une demi-vie in vivo étendue.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)