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1. (WO2018035107) STABILIZED PERTUSSIS ANTIBODIES WITH EXTENDED HALF-LIFE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/035107    International Application No.:    PCT/US2017/046917
Publication Date: 22.02.2018 International Filing Date: 15.08.2017
IPC:
A61K 39/40 (2006.01), C07K 16/12 (2006.01)
Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM [US/US]; 201 West 7th Street Austin, TX 78701 (US).
SYNTHETIC BIOLOGICS, INC [US/US]; 9605 Medical Center Dr., Suite 270 Rockville, MD 20850 (US)
Inventors: MAYNARD, Jennifer; (US).
NGUYEN, Annalee; (US).
KALEKO, Michael; (US)
Agent: BYRD, Marshall P.; (US)
Priority Data:
62/375,347 15.08.2016 US
Title (EN) STABILIZED PERTUSSIS ANTIBODIES WITH EXTENDED HALF-LIFE
(FR) ANTICORPS ANTI-COQUELUCHE STABILISÉS PRÉSENTANT UNE DEMI-VIE ÉTENDUE
Abstract: front page image
(EN)The present invention relates, in part, to modified humanized antibodies which bind the pertussis toxin protein and their use as therapeutic agents. In particular, the present invention is directed, in part, to improved humanized 1B7 and 11E6 antibodies with extended in vivo half-lives.
(FR)L'invention concerne, en partie, des anticorps humanisés modifiés qui se lient à la protéine anatoxine coquelucheuse, et leur utilisation comme agents thérapeutiques. En particulier, l'invention concerne, en partie, des anticorps 1B7 et 11E6 humanisés améliorés présentant une demi-vie in vivo étendue.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)