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1. (WO2018035084) MONOVALENT ASYMMETRIC TANDEM FAB BISPECIFIC ANTIBODIES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/035084 International Application No.: PCT/US2017/046875
Publication Date: 22.02.2018 International Filing Date: 15.08.2017
IPC:
A61K 39/395 (2006.01) ,A61K 51/10 (2006.01) ,C07K 16/24 (2006.01) ,C07K 16/46 (2006.01)
Applicants: EPIMAB BIOTHERAPEUTICS, INC.; #56, 1335 Pu Chi Road Shanghai 201112, CN
Inventors: WU, Chengbin; CN
Agent: YANKWICH, Leon, R.; US
BERKA, Thomas, R.; US
O'BRIEN, David, G.; US
WESOLOWSKI, Michael, R.; US
Priority Data:
PCT/CN2016/009554616.08.2016CN
PCT/CN2016/010926709.12.2016CN
Title (EN) MONOVALENT ASYMMETRIC TANDEM FAB BISPECIFIC ANTIBODIES
(FR) ANTICORPS BISPÉCIFIQUES DE FAB EN TANDEM MONOVALENTS ASYMÉTRIQUES
Abstract: front page image
(EN) The invention provides monovalent, asymmetric tandem Fab bispecific antibodies that can bind two epitopes or two antigens, compositions comprising such antibodies, uses of such antibodies, methods of making such antibodies, nucleic acids encoding such antibodies, and host cells comprising such nucleic acids.
(FR) L'invention concerne des anticorps bispécifiques de Fab en tandem monovalents asymétriques qui peuvent lier deux épitopes ou deux antigènes, des compositions comprenant ces anticorps, des utilisations de ces anticorps, des méthodes de fabrication de ces anticorps, des acides nucléiques codant ces anticorps, et des cellules hôtes comprenant ces acides nucléiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)