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1. (WO2018035050) PURE HEPTASULFATED DISACCHARIDES HAVING IMPROVED ORAL BIOAVAILABILITY

Pub. No.:    WO/2018/035050    International Application No.:    PCT/US2017/046774
Publication Date: Fri Feb 23 00:59:59 CET 2018 International Filing Date: Tue Aug 15 01:59:59 CEST 2017
IPC: C07H 1/00
C07H 11/00
A61K 9/00
A61K 31/7024
A61P 11/06
A61P 11/00
A61P 29/00
Applicants: OPKO PHARMACEUTICALS, LLC
AHMED, Tahir
GUTMAN, Arie
FEDOTEV, Irina
RUKHMAN, Igor
GROSSMAN, Olga
Inventors: AHMED, Tahir
GUTMAN, Arie
FEDOTEV, Irina
RUKHMAN, Igor
GROSSMAN, Olga
Title: PURE HEPTASULFATED DISACCHARIDES HAVING IMPROVED ORAL BIOAVAILABILITY
Abstract:
Hypersulfated disaccharides with utility in asthma or asthma related disorders are disclosed. The heptasulfated disaccharides administered orally have comparable bioavailability to the intravenous administered dosage form.