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1. (WO2018035041) CONTROL ANGIOGENESIS BY REGULATING PHOSPHORYLATION OF SERYL-TRNA SYNTHETASE (SERRS)
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/035041    International Application No.:    PCT/US2017/046754
Publication Date: 22.02.2018 International Filing Date: 14.08.2017
IPC:
C12N 9/00 (2006.01), C07K 16/40 (2006.01)
Applicants: THE SCRIPPS RESEARCH INSTITUTE [US/US]; 10550 North Torrey Pines Road La Jolla, CA 92037 (US)
Inventors: YANG, Xiang-Lei; (US).
SHI, Yi; (CN).
LIU, Ze; (US)
Agent: FITTING, Thomas; (US)
Priority Data:
62/375,592 16.08.2016 US
Title (EN) CONTROL ANGIOGENESIS BY REGULATING PHOSPHORYLATION OF SERYL-TRNA SYNTHETASE (SERRS)
(FR) RÉGULATION DE L'ANGIOGENÈSE PAR RÉGULATION DE LA PHOSPHORYLATION DE LA SERYL-ARNT SYNTHÉTASE (SERRS)
Abstract: front page image
(EN)Disclosed herein are methods and compositions for modulating angiogenesis, and reducing tumor progression by regulating phosphorylation, of seryl-tRNA synthase (SerRS), Also disclosed are related compositions and methods for treating diseases such as cancer.
(FR)L'invention concerne des méthodes et des compositions de modulation de l'angiogenèse, et de réduction de la progression tumorale par régulation de la phosphorylation de la seryl-ARNt synthase (SerRS). L'invention concerne également des compositions et des méthodes associées de traitement de maladies telles que le cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)