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1. (WO2018034522) CONJUGATE COMPRISING CORE AND SIALIC ACID, SIALYLLACTOSE, OR DERIVATIVES OF SAME, BONDED TO SURFACE OF CORE, AND USE THEREOF

Pub. No.:    WO/2018/034522    International Application No.:    PCT/KR2017/008986
Publication Date: Fri Feb 23 00:59:59 CET 2018 International Filing Date: Fri Aug 18 01:59:59 CEST 2017
IPC: A61K 47/58
A23L 33/10
Applicants: KABIO R&D SOO CO., LTD.
주식회사 고암바이오알앤디수
RENSSELAER POLYTECHNIC INSTITUTE
렌슬러 폴리테크닉 인스티튜트
Inventors: KWAK, Jong Hwan
곽종환
NA, Dong Hee
나동희
KWON, Seok Joon
권석준
LINHARDT, J Robert
린드하드,제이로버트
DORDICK, S Jonathan
도르딕 에스 조나단
ZHANG, Fuming
장푸밍
Title: CONJUGATE COMPRISING CORE AND SIALIC ACID, SIALYLLACTOSE, OR DERIVATIVES OF SAME, BONDED TO SURFACE OF CORE, AND USE THEREOF
Abstract:
The present invention relates to a conjugate comprising a core and sialic acid, sialyllactose, or derivatives of same, bonded to the surface of the core, and a use thereof. The conjugate provided by the present invention inhibits the infection process of an influenza virus by binding to the hemagglutinin present on the surface of the influenza virus, thus is not only capable of preventing or treating an influenza virus infection but also capable of preventing or treating infections with influenza viruses exhibiting a tolerance to anti-virus formulations, and can therefore be widely used in the development of formulations for preventing or treating influenza virus infections.