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1. (WO2018034434) VACCINE COMPOSITION CONTAINING CYCLIC PEPTIDE, AND ANTIBODY FOR CYCLIC PEPTIDE OR ANTI-CANCER COMPOSITION CONTAINING SAME
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/034434    International Application No.:    PCT/KR2017/007407
Publication Date: 22.02.2018 International Filing Date: 11.07.2017
IPC:
A61K 39/395 (2006.01), C07K 16/18 (2006.01), G01N 33/574 (2006.01), A61K 39/00 (2006.01)
Applicants: INDUSTRY ACADEMIC COOPERATION FOUNDATION, HALLYM UNIVERSITY [KR/KR]; (Okcheon-dong) Hallym University, 1 Hallymdaehak-gil Chuncheon-si Gangwon-do 24252 (KR)
Inventors: KWON, Hyung Joo; (KR).
KIM, Yong Sung; (KR)
Agent: KOO, Hyun-Seo; 9F, 8, Gangnam-daero 66-gil Gangnam-gu Seoul 06253 (KR)
Priority Data:
10-2016-0104343 17.08.2016 KR
Title (EN) VACCINE COMPOSITION CONTAINING CYCLIC PEPTIDE, AND ANTIBODY FOR CYCLIC PEPTIDE OR ANTI-CANCER COMPOSITION CONTAINING SAME
(FR) COMPOSITION VACCINALE CONTENANT UN PEPTIDE CYCLIQUE, ET UN ANTICORPS ANTI-PEPTIDE CYCLIQUE OU UNE COMPOSITION ANTICANCÉREUSE LE CONTENANT
(KO) 사이클릭 펩타이드를 포함하는 백신 조성물, 사이클릭 펩타이드에 대한 항체 또는 이를 포함하는 항암 조성물
Abstract: front page image
(EN)The present invention relates to a vaccine composition containing a cyclic peptide, and an antibody for the cyclic peptide or an anti-cancer composition containing the same. The vaccine composition of the present invention exhibits inhibitory activity against cancer metastasis, and the antibody of the present invention binds to a tumor specific antigen, TM4SF5, with high affinity and remarkably inhibits the growth, metastasis and infiltration of cancer cells expressing the same, thereby being usable in the diagnosis, prevention or treatment of various cancer in which TM4SF5 is expressed.
(FR)La présente invention concerne une composition vaccinale contenant un peptide cyclique, et un anticorps anti-peptide cyclique ou une composition anticancéreuse le contenant. La composition vaccinale selon la présente invention manifeste une activité inhibitrice contre la métastase cancéreuse, et l'anticorps selon la présente invention se lie à un antigène spécifique de tumeur, TM4SF5, à une affinité élevée et inhibe remarquablement la croissance, la métastase et l'infiltration des cellules cancéreuses l'exprimant, ce qui permet de l'utiliser dans le diagnostic, la prévention ou le traitement de divers cancers dans lesquels TM4SF5 est exprimé.
(KO)본 발명은 본 발명은 사이클릭 펩타이드를 포함하는 백신 조성물, 사이클릭 펩타이드에 대한 항체 또는 이를 포함하는 항암 조성물에 관한 것으로, 본 발명의 백신 조성물은 암 전이에 대한 저해활성을 나타내고, 본 발명의 항체는 종양특이항원 TM4SF5에 높은 친화력으로 결합하며, 이를 발현하는 암세포의 성장, 전이 및 침윤을 현저히 억제하므로, TM4SF5를 발현하는 다양한 암의 진단, 예방 또는 치료에 이용될 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)