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1. (WO2018033918) PIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/033918    International Application No.:    PCT/IL2017/050909
Publication Date: 22.02.2018 International Filing Date: 17.08.2017
IPC:
C07D 413/06 (2006.01), C07D 403/06 (2006.01), C07D 409/06 (2006.01), C07D 401/06 (2006.01), A61K 31/435 (2006.01), A61K 31/496 (2006.01), A61K 31/536 (2006.01), A61P 35/00 (2006.01)
Applicants: VIDAC PHARMA LTD. [IL/IL]; 10 Hartom St., Har Hotzvim P. O. Box 45342 9777510 Jerusalem (IL)
Inventors: SALAMA, Paul; (IL).
BECKER, Oren Menahem; (IL).
BEHAR, Vered; (IL)
Agent: SCHINDLER, Yaffa; (IL)
Priority Data:
62/376,396 18.08.2016 US
Title (EN) PIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF
(FR) DÉRIVÉS DE PIPÉRAZINE, COMPOSITIONS PHARMACEUTIQUES ET LEURS PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)The present invention relates to novel piperazine derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially for targeted therapy treatment of hyperproliferative disorders, including benign hyperproliferative disorders, cancer and pre-cancer conditions.
(FR)La présente invention concerne de nouveaux dérivés de pipérazine, des procédés pour leur préparation, des compositions pharmaceutiques comprenant de tels composés, et des procédés d'utilisation de ces composés et compositions, en particulier pour le traitement thérapeutique ciblé de troubles hyperprolifératifs, y compris des troubles hyperprolifératifs bénins, le cancer et des états précancereux.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)