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1. (WO2018033481) IMMEDIATE RELEASE TABLET OF A BENZOTHIOPHENE COMPOUND
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/033481 International Application No.: PCT/EP2017/070422
Publication Date: 22.02.2018 International Filing Date: 11.08.2017
IPC:
A61K 9/20 (2006.01) ,A61K 31/496 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
496
Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
Applicants: H E X A L AKTIENGESELLSCHAFT[DE/DE]; Industriestr. 25 83607 Holzkirchen, DE
Inventors: KREKELER, Andreas; DE
NEUMANN, Dimitri; DE
Agent: PRÜFER & PARTNER MBB; Sohnckestr. 12 81479 Munich, DE
Priority Data:
16184404.816.08.2016EP
Title (EN) IMMEDIATE RELEASE TABLET OF A BENZOTHIOPHENE COMPOUND
(FR) COMPRIMÉ À LIBÉRATION IMMÉDIATE D'UN COMPOSÉ BENZOTHIOPHÈNE
Abstract:
(EN) The present invention discloses an immediate release tablet comprising at least a tablet core, wherein the tablet core comprises at most 20% brexpiprazole relative to the total of the tablet core, and at least one pharmaceutically acceptable excipient, wherein the tablet core is made by direct compression. Also disclosed are a batch of such immediate release tablets, and a process for preparing such immediate release tablets.
(FR) La présente invention concerne un comprimé à libération immédiate comprenant au moins un noyau de comprimé, le noyau du comprimé comprenant au plus 20 % de brexpiprazole par rapport au total du noyau du comprimé, et au moins un excipient pharmaceutiquement acceptable, le noyau du comprimé étant fabriqué par compression directe. L'invention concerne également un lot de tels comprimés à libération immédiate, et un procédé de préparation de tels comprimés à libération immédiate.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)