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1. (WO2018033132) MAGNETIC RESONANCE IMAGING COMPOUND, INTERMEDIATE THEREOF, MAGNETIC RESONANCE IMAGING AGENT AND APPLICATION OF SAME, AND MAGNETIC RESONANCE IMAGING METHOD
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/033132    International Application No.:    PCT/CN2017/098003
Publication Date: 22.02.2018 International Filing Date: 18.08.2017
IPC:
C07D 403/12 (2006.01), A61K 31/4192 (2006.01), A61K 49/10 (2006.01), A61P 35/00 (2006.01), G01N 24/08 (2006.01)
Applicants: BEIJING NEUROSURGICAL INSTITUTE [CN/CN]; PENG, Siyuan Room 411, No.6 Tiantan Xili, Beijing Neurosurgical Institute Beijing 100050 (CN)
Inventors: LIU, Qian; (CN).
ZHANG, Yazhuo; (CN).
YANG, Xiaoxiao; (CN)
Agent: BEIJING TANLULAI PATENT AGENT LTD; PENG, Siyuan Suite 312, Floor 3, Building No.10, Xinxingdongxiang No.15, Xicheng District Beijing 100044 (CN)
Priority Data:
201610695445.5 19.08.2016 CN
Title (EN) MAGNETIC RESONANCE IMAGING COMPOUND, INTERMEDIATE THEREOF, MAGNETIC RESONANCE IMAGING AGENT AND APPLICATION OF SAME, AND MAGNETIC RESONANCE IMAGING METHOD
(FR) COMPOSÉ D'IMAGERIE PAR RÉSONANCE MAGNÉTIQUE, INTERMÉDIAIRE DE CELUI-CI, AGENT D'IMAGERIE PAR RÉSONANCE MAGNÉTIQUE ET SON APPLICATION, ET PROCÉDÉ D'IMAGERIE PAR RÉSONANCE MAGNÉTIQUE
(ZH) 核磁共振显像化合物、其中间体、核磁共振显像剂及应用、以及核磁共振成像方法
Abstract: front page image
(EN)A benzamide methylpyrrolidine or a pharmaceutically acceptable salt or intermediate thereof, a magnetic resonance imaging agent and application of same, and a magnetic resonance imaging method. The benzamide methylpyrrolidine has a general structure represented by formula (I), wherein R1, R2, R3, X1, X2, X3, X4, and Ln are defined in the specification.
(FR)L'invention concerne un benzamide méthylpyrrolidine ou un sel ou un intermédiaire pharmaceutiquement acceptable de celui-ci, un agent d'imagerie par résonance magnétique et son application, et un procédé d'imagerie par résonance magnétique. La benzamide méthylpyrrolidine présente une structure générale représentée par la formule (I), dans laquelle R 1 , R 2 , R 3 , X 1 , X 2 , X 3 , X 4 , et Ln sont définis dans la description.
(ZH)一种苯甲酰胺甲基吡咯烷类化合物或其药学上可接受的盐、其中间体、核磁共振显像剂及应用、以及核磁共振成像方法。所述苯甲酰胺甲基吡咯烷类化合物具有式(I)所示的通式结构,其中,R1、R2、R3、X1、X2、X3、X4、Ln如说明书所定义。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)