Processing

Please wait...

Settings

Settings

Goto Application

1. WO2018032356 - PROCESS FOR PREPARATION OF LACTONE DERIVATIVES AND INTERMEDIATES THEREOF

Publication Number WO/2018/032356
Publication Date 22.02.2018
International Application No. PCT/CN2016/095527
International Filing Date 16.08.2016
IPC
C07D 307/33 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
02not condensed with other rings
26having one double bond between ring members or between a ring member and a non-ring member
30with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
32Oxygen atoms
33in position 2, the oxygen atom being in its keto or unsubstituted enol form
C07D 263/26 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
263Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
02not condensed with other rings
08having one double bond between ring members or between a ring member and a non-ring member
16with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
18Oxygen atoms
20attached in position 2
26with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
CPC
C07D 263/26
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
263Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
02not condensed with other rings
08having one double bond between ring members or between a ring member and a non-ring member
16with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
18Oxygen atoms
20attached in position 2
26with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
C07D 307/33
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
02not condensed with other rings
26having one double bond between ring members or between a ring member and a non-ring member
30with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
32Oxygen atoms
33in position 2, the oxygen atom being in its keto or unsubstituted enol form
Y02P 20/55
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
20Technologies relating to chemical industry
50Improvements relating to the production of bulk chemicals
55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applicants
  • PHARMARESOURCES (SHANGHAI) CO., LTD. [CN]/[CN]
Inventors
  • CHEN, Ping
  • PENG, Shaoping
  • LI, Yinqiang
  • LI, Dafeng
  • DONG, Xuejun
Agents
  • BEYOND ATTORNEYS AT LAW
Priority Data
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PROCESS FOR PREPARATION OF LACTONE DERIVATIVES AND INTERMEDIATES THEREOF
(FR) PROCÉDÉ DE PRÉPARATION DE DÉRIVÉS DE LACTONE ET DE SES INTERMÉDIAIRES
Abstract
(EN)
A novel process for the preparation of lactone derivatives, and intermediates thereof is described. The lactone derivatives are important precursors for the synthesis of anti-hepatitis C virus agents, including sofosbuvir.
(FR)
La présente invention concerne un nouveau procédé pour la préparation de dérivés de lactone et de ses intermédiaires. Les dérivés de lactone sont des précurseurs importants pour la synthèse d'agents anti-virus de l'hépatite C, y compris le sofosbuvir.
Also published as
Latest bibliographic data on file with the International Bureau