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1. (WO2018031680) NOVEL COMPOUNDS, USES AND METHODS FOR THEIR PREPARATION
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/031680    International Application No.:    PCT/US2017/046138
Publication Date: 15.02.2018 International Filing Date: 09.08.2017
IPC:
A61K 31/506 (2006.01), A61K 31/095 (2006.01)
Applicants: FRONTHERA U.S. PHARMACEUTICALS LLC [US/US]; 11526 Sorrento Valley Road Suite D San Diego, CA 92121 (US)
Inventors: JIN, Bohan; (US).
DONG, Qing; (US).
HUNG, Gene; (US)
Agent: BONNEFOUS, Celine M.; (US)
Priority Data:
62/373,304 10.08.2016 US
Title (EN) NOVEL COMPOUNDS, USES AND METHODS FOR THEIR PREPARATION
(FR) NOUVEAUX COMPOSÉS, LEURS UTILISATIONS ET PROCÉDÉS DE PRÉPARATION
Abstract: front page image
(EN)The present disclosure relates to novel compounds HIF-2α inhibitors and pharmaceutical compositions thereof which may be useful in the treatment and/or prevention of various conditions. The present disclosure also provides methods of preparing such HIF-2α inhibitors and compositions, and methods of using the same.
(FR)La présente invention concerne de nouveaux composés inhibiteurs de HIF-2α et des compositions pharmaceutiques les contenant, qui peuvent être utiles dans le traitement et/ou la prévention de divers états pathologiques. La présente invention concerne également des méthodes de préparation desdits composés inhibiteurs de HIF-2α et compositions, et méthodes d'utilisation de ceux-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)