WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2018030862) PHARMACEUTICAL PREPARATION FOR ORAL ADMINISTRATION WITH CONTROLLED DISSOLUTION RATE, THE PREPARATION COMPRISING TAMSULOSIN HYDROCHLORIDE-CONTAINING SUSTAINED-RELEASE PELLETS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/030862    International Application No.:    PCT/KR2017/008800
Publication Date: 15.02.2018 International Filing Date: 11.08.2017
IPC:
A61K 9/16 (2006.01), A61K 47/38 (2006.01), A61K 9/50 (2006.01), A61K 9/48 (2006.01), A61K 31/18 (2006.01), A61K 31/58 (2006.01), A61K 31/4985 (2006.01)
Applicants: HANMI PHARM. CO., LTD. [KR/KR]; 214, Muha-ro, Paltan-myeon, Hwaseong-si, Gyeonggi-do 18536 (KR)
Inventors: KIM, Jae Ho; (KR).
LEE, Benjamin Joon; (KR).
KIM, Jin Cheul; (KR).
KIM, Yong Il; (KR).
PARK, Jae Hyun; (KR).
WOO, Jong Soo; (KR)
Agent: Y.P.LEE, MOCK & PARTNERS; 12F Daelim Acrotel, 13 Eonju-ro 30-gil Gangnam-gu, Seoul 06292 (KR)
Priority Data:
10-2016-0103269 12.08.2016 KR
Title (EN) PHARMACEUTICAL PREPARATION FOR ORAL ADMINISTRATION WITH CONTROLLED DISSOLUTION RATE, THE PREPARATION COMPRISING TAMSULOSIN HYDROCHLORIDE-CONTAINING SUSTAINED-RELEASE PELLETS
(FR) PRÉPARATION PHARMACEUTIQUE POUR ADMINISTRATION ORALE À VITESSE DE DISSOLUTION CONTRÔLÉE, LA PRÉPARATION COMPRENANT DES PASTILLES À LIBÉRATION PROLONGÉE CONTENANT DU CHLORHYDRATE DE TAMSULOSINE
(KO) 탐수로신 염산염 함유 서방성 펠렛을 포함하는 용출률이 제어된 경구투여용 약제학적 제제
Abstract: front page image
(EN)The present invention provides: a pharmaceutical preparation for oral administration with a controlled dissolution rate, the preparation comprising Tamsulosin hydrochloride-containing sustained-release pellets, wherein the sustained-release pellets comprise (i) a Tamsulosin hydrochloride, (ii) hydroxypropyl methylcellulose (HPMC), (iii) an acid-resistant acryl polymer, and (iv) two or more kinds of insoluble diluents; and a preparation method therefor. According to the present invention, the Tamsulosin hydrochloride-containing sustained-release pellets with a predetermined size can be reproducibly produced, thereby controlling the release rate and reducing the size of pellets, thus improving drug compliance.
(FR)La présente invention concerne : une préparation pharmaceutique destinée à être administrée par voie orale avec un taux de dissolution contrôlé, la préparation comprenant des pastilles à libération prolongée contenant du chlorhydrate de tamsulosine, les pastilles à libération prolongée comprenant (i) un chlorhydrate de tamsulosine, (ii) de l'hydroxypropylméthylcellulose (HPMC), (iii) un polymère acrylique résistant aux acides, et (iv) deux types ou plus de diluants insolubles ; et son procédé de préparation. Selon la présente invention, les pastilles à libération prolongée contenant du chlorhydrate de tamsulosine ayant une taille prédéterminée peuvent être produites de manière reproductible, ce qui permet de réguler le taux de libération et de réduire la taille des pastilles, améliorant ainsi l’observance du médicament.
(KO)본 발명은 탐수로신 염산염 함유 서방성 펠렛을 포함하는 용출률이 제어된 경구투여용 약제학적 제제에 관한 것으로서, 상기 서방성 펠렛은 (i) 탐수로신 염산염, (ii) 하이드록시프로필 메틸셀룰로스(HPMC), (iii) 내산성 아크릴 중합체, 및 (iv) 2종류 이상의 불용성 희석제를 포함하는, 경구투여용 약제학적 제제 및 이의 제조방법을 제공한다. 본 발명에 따르면 특정 크기를 갖는 탐수로신 염산염 함유 서방성 펠렛을 재현성 있게 생산가능하여 방출 속도를 제어할 수 있을 뿐만 아니라 그 크기를 감소시켜 복약 순응도를 높일 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)