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1. (WO2018030650) ANTI-OBESITY COMPOSITION CONTAINING CHRYSANTHEMUM LEAF EXTRACT AS ACTIVE INGREDIENT

Pub. No.:    WO/2018/030650    International Application No.:    PCT/KR2017/007449
Publication Date: Fri Feb 16 00:59:59 CET 2018 International Filing Date: Thu Jul 13 01:59:59 CEST 2017
IPC: A61K 36/28
A23L 33/105
Applicants: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
경북대학교 산학협력단
Inventors: CHOI, Myung-Sook
최명숙
RYU, Ri
류리
KIM, Ye Jin
김예진
KWON, Eun-Young
권은영
Title: ANTI-OBESITY COMPOSITION CONTAINING CHRYSANTHEMUM LEAF EXTRACT AS ACTIVE INGREDIENT
Abstract:
The present invention relates to a pharmaceutical composition for preventing, alleviating, or treating obesity, containing a chrysanthemum leaf extract as an active ingredient. By using a chrysanthemum leaf extract according to the present invention, effects of reducing body weight and body fat, reducing the size of adipocytes, inhibiting an increase in the plasma adipokine amount, increasing the rate of energy metabolism, and increasing thermogenesis have been specifically identified in a high fat diet-induced obesity animal model. In addition, even when a low dose of the chrysanthemum leaf extract is administered, an obesity inhibitory effect similar to that of high dose administration has been identified. Therefore, it is expected that the present invention can be effectively used in the alleviation, prevention, or treatment of obesity even with a low dose thereof.