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1. (WO2018030511) METHOD FOR DETECTING PROTEIN PRESENT IN MEMBRANE OF EXOSOME
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/030511 International Application No.: PCT/JP2017/029064
Publication Date: 15.02.2018 International Filing Date: 10.08.2017
Chapter 2 Demand Filed: 07.02.2018
IPC:
G01N 33/574 (2006.01)
Applicants: WAKAYAMA MEDICAL UNIVERSITY[JP/JP]; 811-1, Kimiidera, Wakayama-shi, Wakayama 6418509, JP
Inventors: YOKOYAMA, Shozo; JP
YAMAUE, Hiroki; JP
Agent: TAKASHIMA, Hajime; JP
Priority Data:
2016-15898512.08.2016JP
Title (EN) METHOD FOR DETECTING PROTEIN PRESENT IN MEMBRANE OF EXOSOME
(FR) PROCÉDÉ DE DÉTECTION DE PROTÉINE PRÉSENTE DANS UNE MEMBRANE D'EXOSOMES
(JA) エクソソームの膜に存在するタンパク質の検出方法
Abstract: front page image
(EN) The present invention provides a method for detecting proteins present in membranes of exosomes in a biological sample, wherein the method includes a step for bringing the exosomes isolated from said biological sample into contact with antibodies for said proteins, in a dispersed state in a bovine-serum albumin solution, thus detecting complexes formed of said proteins and said antibodies.
(FR) La présente invention concerne un procédé de détection de protéines présentes dans des membranes d'exosomes dans un échantillon biologique, le procédé comprenant une étape de mise en contact des exosomes isolés dudit échantillon biologique avec des anticorps desdites protéines, dans un état dispersé dans une solution d'albumine de sérum bovin, ce qui permet de détecter des complexes formés desdites protéines et desdits anticorps.
(JA) 本発明は、生体試料中のエクソソームの膜に存在するタンパク質の検出方法であって、ウシ血清アルブミン溶液中に分散させた、該生体試料から単離したエクソソームと、該タンパク質に対する抗体とを接触させ、該タンパク質と該抗体との複合体を検出する工程を含む方法を提供する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)