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1. (WO2018029676) A COMBINATION OF ANTIMICROBIAL PEPTIDES AND ANTIBIOTIC DRUGS FOR TREATING DISEASES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/029676 International Application No.: PCT/IL2017/050869
Publication Date: 15.02.2018 International Filing Date: 07.08.2017
IPC:
A61K 38/17 (2006.01) ,A61P 31/00 (2006.01) ,A61P 31/04 (2006.01) ,C07K 14/435 (2006.01) ,C12N 15/11 (2006.01)
Applicants: OMNIX MEDICAL LTD.[IL/IL]; High-Tech Village, Givat Ram Campus P.O Box 39158 9139101 Jerusalem, IL
Inventors: BACHNOFF, Niv; IL
COHEN-KUTNER, Moshe; IL
Agent: GORDON, Irit; Pearl Cohen Zedek Latzer Baratz P.O. Box 7198 Tel Aviv 6107121, IL
Priority Data:
62/372,35309.08.2016US
Title (EN) A COMBINATION OF ANTIMICROBIAL PEPTIDES AND ANTIBIOTIC DRUGS FOR TREATING DISEASES
(FR) ASSOCIATION DE PEPTIDES ANTIMICROBIENS ET D'ANTIBIOTIQUES POUR LE TRAITEMENT DE MALADIES
Abstract: front page image
(EN) The invention provides a peptide comprising: a core amino acid sequence, which is identical or similar to the amino acid sequence of a member of the Cecropin family in a combination with an antibiotic drug. The invention further provides methods of treating an infection, overcoming inherent or acquired resistance of a microorganism to an antibiotic agent or disinfecting a wound, the methods comprises administering the peptide in combination with the antibiotic drug to a subject in need thereof, wherein the peptide and the antibiotic drug are administered simultaneously or consecutively.
(FR) L'invention concerne un peptide comprenant une séquence d'acides aminés de base, identique ou similaire à la séquence d'acides aminés des membres de la famille des Cécropines, associé à un antibiotique. L'invention concerne en outre des méthodes permettant de traiter une infection, surmonter la résistance inhérente ou acquise d'un micro-organisme à un agent antibiotique, ou désinfecter une plaie, les méthodes comprenant l'administration du peptide en association avec l'antibiotique au patient le nécessitant, le peptide et l'antibiotique étant administrés simultanément ou consécutivement.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)