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1. (WO2018029671) ADHESIVE ORAL DISSOLVED FILMS IN MANAGING ORAL CARE
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Pub. No.: WO/2018/029671 International Application No.: PCT/IL2017/050845
Publication Date: 15.02.2018 International Filing Date: 31.07.2017
IPC:
A61K 47/38 (2006.01) ,A61K 9/00 (2006.01) ,A61K 9/70 (2006.01) ,A61K 47/00 (2006.01) ,A61K 47/30 (2006.01) ,A61K 47/36 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
38
Cellulose; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
70
Web, sheet or filament bases
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
Applicants:
PHARMEDICA LTD. [IL/IL]; 9 Andrei Sacharov Street Park Matam, Bld 25 north P.O. Box 15060 31905 Haifa, IL
Inventors:
RUBIN, Yoram; IL
TAVOR, David; IL
TAN, Hock; US
TAIRY, Odeya; IL
Agent:
GORDON, Irit; IL
Priority Data:
24716108.08.2016IL
Title (EN) ADHESIVE ORAL DISSOLVED FILMS IN MANAGING ORAL CARE
(FR) FILMS À DISSOLUTION ORALE ADHÉSIFS DESTINÉS À L'HYGIÈNE BUCCO-DENTAIRE
Abstract:
(EN) Disclosed is a dissolvable film adapted to adhere to an oral mucosal tissue of a subject, wherein the film comprises at least three indigestible hydrophilic polymers constituting from 35% to 55% of the film dry weight and wherein the at least three polymers comprise xanthan gum and carboxymethyl cellulose (CMC) in a weight ratio of between 1:0.8-1.6, and at least one other cellulose based polymer. Optionally, the film may further include an active agent in an amount of 0.01% to 35% of the film dry weight. Disclosed also is a method for preparing the film and a method for treating or preventing oral conditions comprising implementing the film. Particularly, the film may be applied between dentures and the gums of the user.
(FR) L'invention concerne un film soluble destiné à adhérer à un tissu mucosal buccal d'un sujet, le film comprenant au moins trois polymères hydrophiles non digérables constituant de 35 % à 55 % du poids sec du film, les au moins trois polymères contenant de la gomme de xanthane et de la carboxyméthyle cellulose (CMC) dans un rapport massique de 1:0,8 - 1,6 et au moins un autre polymère à base de cellulose. Le film peut éventuellement comprendre un autre agent actif dans une quantité de 0,01 % à 35 % du poids sec du film. L'invention concerne également un procédé de préparation du film et un procédé de traitement ou de prévention d'une affection bucco-dentaire au moyen du film selon l'invention. Le film peut notamment être appliqué entre la dentition et les gencives de l'utilisateur.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)