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1. (WO2018027252) IMMUNE-MODULATING COMPOUNDS

Pub. No.:    WO/2018/027252    International Application No.:    PCT/AU2016/050726
Publication Date: Fri Feb 16 00:59:59 CET 2018 International Filing Date: Fri Aug 12 01:59:59 CEST 2016
IPC: C07K 19/00
A61K 38/17
C12N 15/62
A61P 35/00
A61P 37/04
A61P 37/02
A61P 31/00
A61P 33/00
Applicants: THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH
Inventors: WYKES, Michelle
Title: IMMUNE-MODULATING COMPOUNDS
Abstract:
Disclosed are compounds for use in modulating immune responses. More particularly, the present invention discloses oligomeric forms of PD-L2 for use in modulating Th1 immune responses. The compounds of the present invention find utility in a range of Th1-mediated disorders including pathogenic infections and hyperproliferative disorders.