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1. (WO2018027205) MODIFIED ANTIBODY-ALBUMIN NANOPARTICLE COMPLEXES FOR CANCER TREATMENT

Pub. No.:    WO/2018/027205    International Application No.:    PCT/US2017/045643
Publication Date: Fri Feb 09 00:59:59 CET 2018 International Filing Date: Sat Aug 05 01:59:59 CEST 2017
IPC: A61K 47/69
A61K 38/38
A61K 39/395
C07K 16/28
Applicants: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Inventors: MARKOVIC, Svetomir N.
NEVALA, Wendy K.
BUTTERFIELD, John Thomas
KNAUER, Daniel Joseph
Title: MODIFIED ANTIBODY-ALBUMIN NANOPARTICLE COMPLEXES FOR CANCER TREATMENT
Abstract:
Described herein are compositions of modified binding agents and modified carrier proteins, as well as nanoparticle complexes comprising modified binding agents and modified carrier proteins with optionally at least one therapeutic agent, and methods of making and using the same, in particular, as a cancer therapeutic.