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1. (WO2018026811) ANTIFUNGAL AGENTS

Pub. No.:    WO/2018/026811    International Application No.:    PCT/US2017/044894
Publication Date: Fri Feb 09 00:59:59 CET 2018 International Filing Date: Wed Aug 02 01:59:59 CEST 2017
IPC: A01N 43/647
A01N 43/38
Applicants: OHIO STATE INNOVATION FOUNDATION
ACADEMIA SINICA
CHEN, Ching-Shih
CHEN, Ying-Lien
CHEN, Yee-Chun
JADHAV, Appaso
Inventors: CHEN, Ching-Shih
CHEN, Ying-Lien
CHEN, Yee-Chun
JADHAV, Appaso
Title: ANTIFUNGAL AGENTS
Abstract:
Described herein are methods employing substituted phenyl-heteroaryl-aryl compounds, and corresponding kits directed to antifungal therapy. The antifungal activity is tolerant of a wide diversity of fungal species, being effective against Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus, Trichophyton rubrum, and Fusarium solani. Accordingly, the antifungal methods and kits may be generally applicable to a wide range of fungal pathogens.