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1. (WO2018026767) USE OF OXYGENATED CHOLESTEROL SULFATES (OCS) TO TREAT INFLAMMATORY SKIN DISEASE AND SKIN LESIONS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/026767 International Application No.: PCT/US2017/044821
Publication Date: 08.02.2018 International Filing Date: 01.08.2017
IPC:
A01N 1/02 (2006.01) ,A61K 31/575 (2006.01)
Applicants: VIRGINIA COMMONWEALTH UNIVERSITY[US/US]; 800 East Leigh Street Sute 3000 Richmond, VA 23298, US
DURECT CORPORATION[US/US]; Corporate Headquarters 10260 Bubb Road Cupertino, CA 95014-4166, US
Inventors: REN, Shunlin; US
LIN, WeiQi; US
BROWN, James E.; US
THEEUWES, Felix; US
KIM, Mee Jean; US
MIKSZTAL, Andrew R.; US
WU, Hongwei; US
LEE, Min L.; US
SU, Huey-Ching; US
TAMRAZ, Wilma; US
Agent: WHITHAM, Michael E.; US
CURTIS, Marshall, M.; US
FIELDS, Whitney, C.; US
TYLER-CROSS, Ruth, E.; US
Priority Data:
62/370,03602.08.2016US
62/470,57613.03.2017US
Title (EN) USE OF OXYGENATED CHOLESTEROL SULFATES (OCS) TO TREAT INFLAMMATORY SKIN DISEASE AND SKIN LESIONS
(FR) UTILISATION DE SULFATES DE CHOLESTÉROL OXYGÉNÉS (OCS) POUR TRAITER DES MALADIES INFLAMMATOIRES DE LA PEAU ET DES LÉSIONS CUTANÉES
Abstract:
(EN) Methods of treating and prophylactically treating inflammatory skin diseases and skin lesions are provided. For instance, the methods may involve contacting the skin with an oxygenated cholesterol sulfate (OCS), e.g. 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or a pharmaceutically acceptable salt thereof.
(FR) L'invention concerne des méthodes de traitement et de traitement prophylactique de maladies cutanées inflammatoires et de lésions cutanées. Par exemple, les méthodes peuvent impliquer la mise en contact de la peau avec un sulfate de cholestérol oxygéné (OCS), par exemple, le 5-cholestène-3, 25-diol, 3-sulfate (25HC3S) ou un sel de celui-ci acceptable sur le plan pharmaceutique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)