Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018026738) ULTRASOUND GUIDED OPENING OF BLOOD-BRAIN BARRIER
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/026738 International Application No.: PCT/US2017/044763
Publication Date: 08.02.2018 International Filing Date: 31.07.2017
IPC:
A61B 8/00 (2006.01) ,A61B 8/06 (2006.01) ,A61B 8/08 (2006.01) ,A61B 8/12 (2006.01) ,A61B 8/14 (2006.01) ,A61B 9/00 (2006.01) ,A61B 8/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
8
Diagnosis using ultrasonic, sonic or infrasonic waves
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
8
Diagnosis using ultrasonic, sonic or infrasonic waves
06
Measuring blood flow
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
8
Diagnosis using ultrasonic, sonic or infrasonic waves
08
Detecting organic movements or changes, e.g. tumours, cysts, swellings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
8
Diagnosis using ultrasonic, sonic or infrasonic waves
12
in body cavities or body tracts, e.g. by using catheters
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
8
Diagnosis using ultrasonic, sonic or infrasonic waves
13
Tomography
14
Echo-tomography
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
9
Instruments for examination by percussion; Pleximeters
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
8
Diagnosis using ultrasonic, sonic or infrasonic waves
04
Measuring blood pressure
Applicants:
RAMAMURTHY, Bhaskar [US/US]; US
Inventors:
RAMAMURTHY, Bhaskar; US
Agent:
POLLEY, Richard, J.; US
Priority Data:
62/369,20801.08.2016US
Title (EN) ULTRASOUND GUIDED OPENING OF BLOOD-BRAIN BARRIER
(FR) OUVERTURE GUIDÉE PAR ULTRASONS DE LA BARRIÈRE HÉMATO-ENCÉPHALIQUE
Abstract:
(EN) A system for delivering drugs or other molecules to the brain comprises an ultrasound imaging transducer configured to image structures such as the circle of Willis within a patient's head by way of a low attenuation acoustic window. The system includes a processor configured to register the ultrasound images to previously obtained images which also include the structures. The system includes ultrasound transducer elements operable to deliver ultrasound energy to a target region to cause the blood brain barrier to open. The system may include a drug delivery system that may be operated to deliver a drug to the patient in coordination with opening the blood brain barrier. Coordinates of the target region relative to the ultrasound imaging transducer are determined using registration information.
(FR) L'invention concerne un système d'administration de médicaments ou d'autres molécules au cerveau, comprenant un transducteur d'imagerie ultrasonore conçu former des images de structures, telles que le cercle artériel de Willys dans la tête d'un patient au moyen d'une fenêtre acoustique à faible atténuation. Le système comprend un processeur conçu pour enregistrer les images ultrasonores sur des images précédemment obtenues qui comprennent également les structures. Le système comprend des éléments transducteurs ultrasonores pouvant fournir de l'énergie ultrasonore à une région cible afin de provoquer l'ouverture de la barrière hémato-encéphalique. Le système peut comprendre un système d'administration de médicament qui peut être actionné pour administrer un médicament au patient en coordination avec l'ouverture de la barrière hémato-encéphalique. Les coordonnées de la région cible par rapport au transducteur d'imagerie ultrasonore sont déterminées à l'aide d'informations d'enregistrement.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)