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1. (WO2018025979) COPOLYMER, AS WELL AS SEPARATION MEMBRANE, MEDICAL DEVICE, AND BLOOD PURIFIER IN WHICH SAID COPOLYMER IS USED
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/025979 International Application No.: PCT/JP2017/028339
Publication Date: 08.02.2018 International Filing Date: 04.08.2017
IPC:
C08F 218/04 (2006.01) ,A61L 33/06 (2006.01) ,A61M 1/16 (2006.01) ,B01D 71/38 (2006.01) ,B01D 71/40 (2006.01) ,B01D 71/44 (2006.01) ,C08F 220/12 (2006.01) ,C08F 226/02 (2006.01) ,C08F 226/10 (2006.01)
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
F
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
218
Copolymers having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an acyloxy radical of a saturated carboxylic acid, of carbonic acid, or of a haloformic acid
02
Esters of monocarboxylic acids
04
Vinyl esters
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
33
Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
06
Use of macromolecular materials
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1
Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14
Dialysis systems; Artificial kidneys; Blood oxygenators
16
with membranes
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
71
Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
06
Organic material
38
Polyalkenylalcohols; Polyalkenylesters; Polyalkenylethers; Polyalkenylaldehydes; Polyalkenylketones; Polyalkenylacetals; Polyalkenylketals
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
71
Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
06
Organic material
40
Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
71
Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
06
Organic material
44
Polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds, not provided for in a single one of groups B01D71/26-B01D71/42177
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
F
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
220
Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide, or nitrile thereof
02
Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
10
Esters
12
of monohydric alcohols or phenols
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
F
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
226
Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
02
by a single or double bond to nitrogen
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
F
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
226
Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
06
by a heterocyclic ring containing nitrogen
10
N-Vinyl-pyrrolidone
Applicants: TORAY INDUSTRIES, INC.[JP/JP]; 1-1, Nihonbashi-Muromachi 2-chome, Chuo-ku, Tokyo 1038666, JP
Inventors: BABA, Takeshi; JP
KAWAKAMI, Tomonori; JP
USHIRO, Suguru; JP
UENO, Yoshiyuki; JP
Priority Data:
2016-15476005.08.2016JP
Title (EN) COPOLYMER, AS WELL AS SEPARATION MEMBRANE, MEDICAL DEVICE, AND BLOOD PURIFIER IN WHICH SAID COPOLYMER IS USED
(FR) COPOLYMÈRE AINSI QUE MEMBRANE DE SÉPARATION, DISPOSITIF MÉDICAL ET PURIFICATEUR DE SANG DANS LESQUELS LEDIT COPOLYMÈRE EST UTILISÉ
(JA) 共重合体並びにそれを用いた分離膜、医療デバイス及び血液浄化器
Abstract:
(EN) The purpose of the present invention is to provide a copolymer having exceptional water permeability, platelet adherence suppression, and protein adherence suppression, and to provide a separation membrane, a medical device, and a medical separation membrane module in which said copolymer is used. The present invention provides a copolymer containing monomer units derived from two or more types of monomer, wherein the hydration energy density of the copolymer is 158.992 to 209.200 kJ・mol‒1・nm‒3, the monomer unit having the highest hydration energy density among the monomer units does not include a hydroxy group, the volume fraction of monomer units having the highest hydration energy density among the monomer units is 35 to 90%, and the difference in hydration energy density is 71.128 to 418.400 kJ・mol‒1・nm‒3.
(FR) Le but de la présente invention concerne un copolymère présentant une perméabilité exceptionnelle à l'eau, une suppression de l'adhérence des plaquettes et une suppression de l'adhérence des protéines et une membrane de séparation, un dispositif médical et un module de membrane de séparation médicale dans lesquels ledit copolymère est utilisé. La présente invention concerne un copolymère contenant des motifs monomères dérivés de deux types, ou plus, de monomères, la densité d'énergie d'hydratation du copolymère étant de 158.992 à 209.200 kJ・mol‒1・nm‒3, le motif monomère présentant la densité d'énergie d'hydratation la plus élevée parmi les motifs monomères ne comprenant pas de groupe hydroxy, la fraction volumique de motifs monomères présentant la densité d'énergie d'hydratation la plus élevée parmi les motifs monomères étant de 35 à 90% et la différence de densité d'énergie d'hydratation étant de 71.128 à 418.400 kJ・mol‒1・nm‒3.
(JA) 本発明は、透水性、血小板付着抑制、タンパク質付着抑制に優れた共重合体並びにそれを用いた分離膜、医療デバイス、医療用分離膜モジュールを提供することを目的としている。本発明は、2種類以上のモノマーに由来するモノマー単位を含有する共重合体であって、上記共重合体の水和エネルギー密度は、158.992~209.200kJ・mol-1・nm-3であり、上記モノマー単位において、水和エネルギー密度が最も大きいモノマー単位は、ヒドロキシ基を含まないモノマー単位であり、上記モノマー単位において、水和エネルギー密度が最も大きいモノマー単位の体積分率は、35~90%であり、水和エネルギー密度の差が、71.128~418.400kJ・mol-1・nm-3である、共重合体を提供する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)