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1. (WO2018025049) NEW USE OF N,N-BIS-2-MERCAPTOETHYL ISOPHTHALAMIDE
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Pub. No.: WO/2018/025049 International Application No.: PCT/GB2017/052306
Publication Date: 08.02.2018 International Filing Date: 04.08.2017
Chapter 2 Demand Filed: 29.05.2018
IPC:
A61K 45/06 (2006.01) ,A61K 31/166 (2006.01) ,A61K 31/167 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
165
having aromatic rings, e.g. colchicine, atenolol, progabide
166
having the carbon atom of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
165
having aromatic rings, e.g. colchicine, atenolol, progabide
167
having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
Applicants:
EMERAMED LIMITED [IE/IE]; Trinity House Charleston Road Ranelagh Dublin 6, IE
Inventors:
HALEY, Boyd Eugene; US
KLINGBERG, Ragnar Axel Theodor; SE
Agent:
MCNEENEY, Stephen Phillip; GB
Priority Data:
1613535.205.08.2016GB
Title (EN) NEW USE OF N,N-BIS-2-MERCAPTOETHYL ISOPHTHALAMIDE
(FR) NOUVELLE UTILISATION DU N,N-BIS-2-MERCAPTOÉTHYL-ISOPHTALAMIDE
Abstract:
(EN) There is provided the compound N,N-bis-2-mercaptoethyl isophthalamide (NBMI), or a pharmaceuticaliy-acceptable salt and/or derivative thereof, for use in the treatment or prevention of paracetamol toxicity. Such compounds have particular utility in the treatment or prevention of acute liver failure associated with paracetamol toxicity.
(FR) La présente invention concerne le composé N,N-bis-2-mercaptoéthyl-isophtalamide (NBMI), ou un sel pharmaceutiquement acceptable et/ou un dérivé de celui-ci, pour utilisation dans le traitement ou la prévention de la toxicité du paracétamol. De tels composés sont particulièrement utiles dans le traitement ou la prévention d’une insuffisance hépatique aiguë liée à la toxicité du paracétamol.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)