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1. (WO2018023827) PROTECTIVE FLUID FOR ENDOMETRIAL STEM CELL
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/023827    International Application No.:    PCT/CN2016/094673
Publication Date: 08.02.2018 International Filing Date: 11.08.2016
IPC:
A01N 1/02 (2006.01)
Applicants: BEIJING ZHEN HUIKANG BIOLOGICAL TECHNOLOGY CO., LTD. [CN/CN]; No. 31, Professional Garden Xishiku Street, Xicheng Beijing 100034 (CN)
Inventors: CAO, Yulin; (CN).
LIN, Juntang; (CN).
LI, Xiayun; (CN).
LIU, Shihong; (CN).
LU, Chengqian; (CN)
Agent: BEIJING AIPUNAJIE PATENT FIRM; WANG, Yusong Room 208, Two Floor, 25 Tower No. 1, Dongdadi Street, Dongcheng Beijing 100061 (CN)
Priority Data:
201610622766.2 01.08.2016 CN
Title (EN) PROTECTIVE FLUID FOR ENDOMETRIAL STEM CELL
(FR) FLUIDE PROTECTEUR POUR CELLULE SOUCHE ENDOMÉTRIALE
(ZH) 一种宫内膜干细胞保护液
Abstract: front page image
(EN)Provided is a protective fluid for an endometrial stem cell. The protective fluid is primarily prepared by dissolving an anti-hypoxia protective agent, mycoplasma inhibiting agent, and aminoglycoside antibiotic in an aqueous solution of a DMEM/F12 growth medium. Every milliliter of the aqueous medium of the DMEM/F12 growth medium comprises the following dissolved components: 3-15 mg of the anti-hypoxia protective agent, 1-20 mg of the mycoplasma inhibiting agent, and 100-500 U of the aminoglycoside antibiotic. The aqueous medium of the DMEM/F12 growth medium has a concentration of 20-45 mg/mL. The protective fluid can increase the survivability of the endometrial stem cell during storage and improve cell quality.
(FR)L'invention concerne un fluide protecteur pour une cellule souche endométriale. Le fluide protecteur est préparé principalement par dissolution d'un agent protecteur anti-hypoxie, d'un agent inhibiteur de mycoplasme et d'un antibiotique aminoglycoside dans une solution aqueuse d'un milieu de croissance DMEM/F12. Chaque millilitre du milieu aqueux du milieu de croissance DMEM/F12 comprend les composants dissous suivants: 3 à 15 mg de l'agent protecteur anti-hypoxie, 1 à 20 mg de l'agent inhibiteur de mycoplasme, et 100 à 500 U de l'antibiotique aminoglycoside. Le milieu aqueux du milieu de croissance DMEM/F12 présente une concentration de 20 à 45 mg/mL. Le fluide protecteur peut augmenter la capacité de survie de la cellule souche endométriale pendant l'entreposage et améliorer la qualité des cellules.
(ZH)提供一种宫内膜干细胞保护液,所述保护液主要是将低氧保护剂、支原体抑制剂以及氨基糖苷类抗生素用DMEM/F12培养基水溶液溶解而成,每毫升所述DMEM/F12培养基水溶液分别溶解所述低氧保护剂3-15mg、所述支原体抑制剂1-20mg以及氨基糖苷类抗生素100-500U,所述DMEM/F12培养基水溶液的浓度为20-45mg/ml。该保护液可提高存储的宫内膜干细胞存活率,提高细胞质量。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)