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1. (WO2018022936) CLOSTRIDIUM DIFFICILE TARGETING MOIETIES AND CONSTRUCTS COMPRISING SAID MOIETIES
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Pub. No.: WO/2018/022936 International Application No.: PCT/US2017/044248
Publication Date: 01.02.2018 International Filing Date: 27.07.2017
IPC:
A61K 38/16 (2006.01) ,C07K 14/435 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
Applicants:
C3 JIAN, LLC [US/US]; 4503 Glencoe Avenue Marina Del Rey, California 90292, US
Inventors:
LEE, Shaoying; US
BAUDYS, Miroslav; US
ECKERT, Randal H.; US
VARNUM, Brian C.; US
Agent:
HUNTER, Tom; US
WEAVER, Jeffrey K.; US
AUSTIN, James E.; US
VILLENEUVE, Joseph M.; US
SAMPSON, Roger S.; US
GRIFFITH, John F.; US
BERGIN, Denise S.; US
SCHOLZ, Christian D.; US
Priority Data:
62/368,97029.07.2016US
Title (EN) CLOSTRIDIUM DIFFICILE TARGETING MOIETIES AND CONSTRUCTS COMPRISING SAID MOIETIES
(FR) FRACTIONS DE CIBLAGE DE CLOSTRIDIUM DIFFICILE ET CONSTRUCTIONS COMPRENANT LESDITES FRACTIONS
Abstract:
(EN) In certain embodiments, constructs are provided that selectively/preferentially inhibit and/or kill Clostridium difficile. In certain embodiments the constructs comprise a peptide that binds C. difficile attached directly or through an amino acid or a linker to an antimicrobial peptide.
(FR) Dans certains modes de réalisation, l'invention concerne des constructions qui inhibent et/ou éliminent de façon sélective/préférentielle Clostridium difficile. Dans certains modes de réalisation, les constructions selon l'invention comprennent un peptide qui se lie à C. difficile, fixé directement ou par l'intermédiaire d'un acide aminé ou d'un lieur à un peptide antimicrobien.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)