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1. (WO2018022637) CREBBP RELATED CANCER THERAPY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/022637 International Application No.: PCT/US2017/043757
Publication Date: 01.02.2018 International Filing Date: 25.07.2017
IPC:
C12N 9/10 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10
Transferases (2.)
Applicants: EPIZYME, INC.[US/US]; 400 Technology Square Cambridge, Massachusetts 02139, US
Inventors: GRASSIAN, Alexandra; US
RIBICH, Scott; US
SMITH, Jesse; US
HARVEY, Darren; US
Agent: VETTER, Michael L.; US
AUGST, Alexander D.; US
BUTEAU, Kristen C.; US
CAHILL, John J.; US
HAULBROOK, William R.; US
LUCA, Cassandra Gianna; US
JARRELL, Brenda Herschbach; US
KLEIN, Daniel A.; US
LI, Xiaodong; US
LYON, Charles E.; US
MEDINA, Rolando; US
MONROE, Margo R.; US
NGUYEN, Suzanne P.; US
PACE, Nicholas J.; US
PYSHER, Paul A.; US
REARICK, John P.; US
REESE, Brian E.; US
ROHLFS, Elizabeth M.; US
SAHR, Robert N.; US
SCHONEWALD, Stephanie L.; US
SHAIKH, Nishat A.; US
SHINALL, Michael A.; US
SHORE, David E.; US
SMITH, Maria C.; US
SUH, Su Kyung; US
VRABLIK, Tracy L.; US
WANG, Gang; US
Priority Data:
62/366,24925.07.2016US
Title (EN) CREBBP RELATED CANCER THERAPY
(FR) CANCÉROTHÉRAPIE ASSOCIÉE À CREBBP
Abstract:
(EN) The present disclosure provides novel cancer therapies. The treatment of cancers harboring EP300 mutations with CREBBP inhibition therapy is described.
(FR) La présente invention concerne de nouvelles cancérothérapies. Le traitement de cancers présentant des mutations du gène EP300 grâce à une thérapie inhibitrice de CREBBP est décrit.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)