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1. (WO2018022608) NOVEL ADENO-ASSOCIATED VIRUS CAPSID PROTEINS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/022608    International Application No.:    PCT/US2017/043703
Publication Date: 01.02.2018 International Filing Date: 25.07.2017
IPC:
C07K 14/005 (2006.01), C12N 15/86 (2006.01), A61K 48/00 (2006.01)
Applicants: BIOMARIN PHARMACEUTICAL INC. [US/US]; 105 Digital Drive Novato, CA 94949 (US)
Inventors: COLOSI, Peter, Cameron; (US).
LOCHRIE, Michael; (US).
NG, Robert; (US)
Agent: SINTICH, Sharon, M.; (US)
Priority Data:
62/366,838 26.07.2016 US
Title (EN) NOVEL ADENO-ASSOCIATED VIRUS CAPSID PROTEINS
(FR) NOUVELLES PROTÉINES DE CAPSIDE DE VIRUS ADÉNO-ASSOCIÉS
Abstract: front page image
(EN)The invention relates to novel adeno-associated virus (AAV) capsid proteins, AAV particles comprising a novel capsid protein, polynucleotides encoding these capsid proteins and AAV vectors expressing these capsid proteins. The invention also relates to methods of making the herein described AAV vectors expressing the novel capsid proteins of the invention and associated therapeutic uses of thereof.
(FR)L'invention concerne de nouvelles protéines de capside de virus adéno-associés (AAV), des particules d'AAV comprenant une nouvelle protéine de capside, des polynucléotides codant pour ces protéines de capside et des vecteurs AAV exprimant ces protéines de capside. L'invention concerne également des procédés de fabrication des vecteurs AAV décrits dans la description exprimant les nouvelles protéines de capside de l'invention et leurs utilisations thérapeutiques associées.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)