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1. (WO2018020242) PHARMACEUTICAL COMPOUNDS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/020242    International Application No.:    PCT/GB2017/052178
Publication Date: 01.02.2018 International Filing Date: 26.07.2017
IPC:
C07D 401/14 (2006.01), C07D 405/14 (2006.01), C07D 413/14 (2006.01), C07D 401/04 (2006.01), C07D 409/14 (2006.01), C07D 491/10 (2006.01), A61K 31/4412 (2006.01), A61K 31/4427 (2006.01), A61K 31/513 (2006.01), A61P 19/00 (2006.01), A61P 25/16 (2006.01), A61P 35/00 (2006.01)
Applicants: ALMAC DISCOVERY LIMITED [GB/GB]; Almac House 20 Seagoe Industrial Estate Craigavon BT63 5QD (GB)
Inventors: HEWITT, Peter; (GB).
MCFARLAND, Mary Melissa; (GB).
ROUNTREE, James Samuel Shane; (GB).
BURKAMP, Frank; (GB).
BELL, Christina; (GB).
PROCTOR, Lauren; (GB).
HELM, Matthew Duncan; (GB).
O'DOWD, Colin; (GB).
HARRISON, Timothy; (GB)
Agent: BOULT WADE TENNANT; Verulam Gardens 70 Gray's Inn Road London WC1X 8BT (GB)
Priority Data:
1612938.9 26.07.2016 GB
Title (EN) PHARMACEUTICAL COMPOUNDS
(FR) COMPOSÉS PHARMACEUTIQUES
Abstract: front page image
(EN)The present invention relates to compounds of Formula (I) that are useful as inhibitors of the activity of the ubiquitin specific protease USP19. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in therapy.
(FR)La présente invention concerne des composés de formule (I) utilisés comme inhibiteurs de l'activité de la protéase spécifique de l'ubiquitine USP19. La présente invention concerne également des compositions pharmaceutiques contenant ces composés, ainsi que des méthodes d'utilisation de ces composés dans un traitement.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)