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1. (WO2018020222) INHIBITORS OF THE MMRN2 INTERACTION WITH CLEC14A AND/OR CD93
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/020222    International Application No.:    PCT/GB2017/052154
Publication Date: 01.02.2018 International Filing Date: 24.07.2017
IPC:
C07K 14/78 (2006.01), A61K 39/00 (2006.01), C07K 16/30 (2006.01), C07K 14/47 (2006.01)
Applicants: THE UNIVERSITY OF BIRMINGHAM [GB/GB]; Edgbaston Birmingham B15 2TT (GB)
Inventors: BICKNELL, Roy; (GB).
KHAN, Kabir, Ali; (GB)
Agent: PEARS, Michael; Potter Clarkson LLP The Belgrave Centre Talbot Street Nottingham NG1 5GG (GB)
Priority Data:
1612860.5 25.07.2016 GB
Title (EN) INHIBITORS OF THE MMRN2 INTERACTION WITH CLEC14A AND/OR CD93
(FR) INHIBITEURS
Abstract: front page image
(EN)The invention provides a portion of multimerin 2 (MMRN2) or a variant thereof, that inhibits the interaction between CLEC14A and MMRN2, in addition to a portion of MMRN2 or a variant thereof, that inhibits the interaction between CD93 and MMRN2. The invention provides compounds comprising said portions and either a cytotoxic moiety or a detectable moiety.
(FR)L'invention concerne une partie de multimérine 2 (MMRN2) ou un variant de celle-ci, qui inhibe l'interaction entre CLEC14A et MMRN2, en plus d'une partie de MMRN2 ou d'un variant de celle-ci, qui inhibe l'interaction entre CD93 et MMRN2. L'invention concerne des composés comprenant lesdites parties et, soit une fraction cytotoxique, soit une fraction détectable.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)