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1. (WO2018019929) PIPERIDINE CXCR7 RECEPTOR MODULATORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/019929    International Application No.:    PCT/EP2017/068990
Publication Date: 01.02.2018 International Filing Date: 27.07.2017
IPC:
C07D 413/14 (2006.01), A61K 31/4545 (2006.01), A61K 31/506 (2006.01), A61P 29/00 (2006.01), A61P 35/00 (2006.01), A61P 43/00 (2006.01)
Applicants: IDORSIA PHARMACEUTICALS LTD [CH/CH]; Hegenheimermattweg 91 4123 Allschwil (CH)
Inventors: AISSAOUI, Hamed; (CH).
GUERRY, Philippe; (CH).
LEHEMBRE, Francois; (CH).
POTHIER, Julien; (CH).
POUZOL, Laetitia; (CH).
RICHARD-BILDSTEIN, Sylvia; (CH).
YUAN, Shuguang; (CH)
Agent: VELKER, Jörg; (CH)
Priority Data:
PCT/EP2016/068052 28.07.2016 EP
Title (EN) PIPERIDINE CXCR7 RECEPTOR MODULATORS
(FR) MODULATEURS DU RÉCEPTEUR DE CXCR7 PIPÉRIDINE
Abstract: front page image
(EN)The present invention relates to piperidine derivatives of formula (I) wherein Ar1, Ar2, RAr1, R1, R2, and R3 are as described in the description, their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as CXCR7 receptor modulators.
(FR)La présente invention concerne des dérivés de pipéridine de la formule (I) dans laquelle Ar1, Ar2, RAr1, R1, R2, et R3 sont tels que définis dans la description, ainsi que leur préparation, des sels pharmaceutiquement acceptables de ceux-ci et leur utilisation en tant que produits pharmaceutiques, à des compositions pharmaceutiques contenant au moins un composé de formule (I), et en particulier leur utilisation comme modulateurs du récepteur CXCR7.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)