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1. (WO2018019772) CHIMERIC ANTIGEN RECEPTOR
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/019772    International Application No.:    PCT/EP2017/068654
Publication Date: 01.02.2018 International Filing Date: 24.07.2017
Chapter 2 Demand Filed:    04.04.2018    
IPC:
A61K 39/00 (2006.01), C07K 16/30 (2006.01), C12N 5/0783 (2010.01)
Applicants: TESSA THERAPEUTICS PTE. LTD. [SG/SG]; 8 Temasek Boulevard #24-02 Suntec Tower Three Singapore 038988 (SG).
RICHARD IAN CLEGG [GB/GB]; City Tower 40 Basinghall Street London Greater London EC2V 5DE (GB) (LS only)
Inventors: CONNOLLY, John Edward; (SG).
VU, Dang L.; (SG)
Agent: CLEGG, Richard; (GB).
ADDISS, John; (GB).
ANDREWS, Robert; (GB).
BAILEY, Sam; (GB).
BRASNETT, Adrian; (GB).
BREARLEY, Sarah; (GB).
CARLISLE, Julie; (GB).
CARTER, Stephen; (GB).
CASLEY, Christopher; (GB).
CRIPPS, Joanna; (GB).
DALE, Elizabeth; (GB).
DENISON, Christopher; (GB).
DUNNE, Paul; (GB).
FORREST, Graham; (GB).
GILL, Stephen; (GB).
GRAHAM, Emma; (GB).
GREEN, Katherine; (GB).
GREGORY, Adam; (GB).
HARRISON, Susan; (GB).
HAYES, Emily; (GB).
HODSDON, Stephen; (GB).
JOHNSON, Richard; (GB).
JONES, Rachel; (GB).
KEIRSTEAD, Tanis; (GB).
KIDDLE, Simon; (GB).
KREMER, Simon; (GB).
LEACH, James; (GB).
LENTHALL, Joseph; (GB).
LYONS, June; (GB).
MCGUINN, Callum; (GB).
MOORE, Graeme; (GB).
NAYLOR, Matthew; (GB).
OXLEY, Rachel; (GB).
PARRY, Simon; (GB).
SALISBURY, Frances; (GB).
SMITH, Matthew; (GB).
STONER, Patrick; (GB).
SUTCLIFFE, Nicholas; (GB).
TOLLERVEY, Rebecca; (GB).
WALTON, Seán; (GB).
WARD, Eliot; (GB).
WATSON, Robert; (GB).
WEBSTER, Jeremy; (GB).
WESCOTT, Rhiannon; (GB).
WILLS, Jonathan; (GB).
WOOLLEY, Lindsey; (GB).
WYTENBURG, Wilhelmus; (GB)
Priority Data:
62/366,729 26.07.2016 US
62/366,731 26.07.2016 US
Title (EN) CHIMERIC ANTIGEN RECEPTOR
(FR) RÉCEPTEUR D'ANTIGÈNES CHIMÉRIQUE
Abstract: front page image
(EN)Chimeric Antigen Receptors (CARs) comprising a costimulatory sequence which is, or which is derived from, the intracellular domain of CD226, or a fragment thereof, are disclosed. Also disclosed are compositions comprising such CARs, and uses and methods using the same.
(FR)L'invention concerne des récepteurs d'antigènes chimériques (CAR) comprenant une séquence co-stimulatrice qui est ou qui est dérivée du domaine intracellulaire de CD226, ou d'un fragment de celui-ci. L'invention concerne également des compositions comprenant ces CAR, ainsi que des utilisations et des méthodes d'utilisation de celles-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)