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1. (WO2018019284) COMPOUNDS FOR ENHANCING BAX/BCL-2 EXPRESSION AND ACTIVITY AND THERAPEUTIC USE THEREOF

Pub. No.:    WO/2018/019284    International Application No.:    PCT/CN2017/094855
Publication Date: Fri Feb 02 00:59:59 CET 2018 International Filing Date: Sat Jul 29 01:59:59 CEST 2017
IPC: A61K 31/519
A61P 35/00
Applicants: REALINN LIFE SCIENCE LIMITED
Inventors: LIN, Jen Cheng
TSAI, Jui-Chi
HSIEH, Pei Jung
DU, Ying-Chi
Title: COMPOUNDS FOR ENHANCING BAX/BCL-2 EXPRESSION AND ACTIVITY AND THERAPEUTIC USE THEREOF
Abstract:
The use of a therapeutically effective amount of a compound of formula (I) in preparing medicines for preventing or treating BAX/BCL-2-related disorders, including cancers, myeloproliferative disorder, prostate epithelial dysplasia, lymphangioleiomyomatosis, Kimura disease and keloid.