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1. (WO2018019252) NOVEL FUSED PYRIDINE DERIVATIVES USEFUL AS FAK/AURORA KINASE INHIBITORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/019252    International Application No.:    PCT/CN2017/094474
Publication Date: 01.02.2018 International Filing Date: 26.07.2017
IPC:
C07D 401/12 (2006.01), C07D 413/12 (2006.01), C07D 405/12 (2006.01), C07D 401/14 (2006.01), C07D 239/48 (2006.01), C07D 403/12 (2006.01), A61K 31/506 (2006.01), A61P 37/00 (2006.01), A61P 29/00 (2006.01)
Applicants: JACOBIO PHARMACEUTICALS CO., LTD. [CN/CN]; Unit 2, Building 5, BYBP, No. 88 Kechuang Street 6th Business Development Area, Daxing Beijing 101111 (CN)
Inventors: ZHOU, Wenlai; (CN).
LI, Runze; (CN).
GAO, Panliang; (CN).
WU, Xinping; (CN).
BAI, Jinlong; (CN).
YANG, Guiqun; (CN).
WANG, Yanping; (CN).
KANG, Di; (CN)
Priority Data:
PCT/CN2016/091693 26.07.2016 CN
Title (EN) NOVEL FUSED PYRIDINE DERIVATIVES USEFUL AS FAK/AURORA KINASE INHIBITORS
(FR) NOUVEAUX DÉRIVÉS DE PYRIDINE FUSIONNÉS UTILES EN TANT QU'INHIBITEURS DE LA KINASE FAK/AURORA
Abstract: front page image
(EN)This invention relates to certain novel pyrimidine derivatives of the Formula (I). The invention also relates to process for the preparation of the compound of the formula (I), pharmaceutical agents or compositions containing the compound or a method of using the compound for the treatment of proliferative diseases, such as cancer.
(FR)Cette invention concerne certains nouveaux dérivés de pyrimidine de formule (I). L'invention porte également sur des procédés de préparation du composé représenté par la formule (I), des agents ou des compositions pharmaceutiques contenant le composé ou un procédé d'utilisation du composé pour le traitement de maladies prolifératives, telles que le cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)